CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM108
Family Name Adenosine kinase inhibitor AGN-PC-074UAJ family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00307220 Functional Category Bioactive
Superfamily Adenosine kinase and Epidermal growth factor receptor Binder Superfamily
Class Class 920

Cousin Family NamesSeedsMembers
Interleukin-12 subunit alpha Inhibitor STA-5326 Family 2 51
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor PF-0048... 2 13
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Adenosine receptor A3 and Adenosine receptor A2a ligand 5-buty... 3 13
Adenosine kinase inhibitor abt-702 family 14 1
Adenosine kinase inhibitor 3-[1-[5-[4-amino-5-(3-bromophenyl)p... 1 0
Corticotropin-releasing factor receptor 1 ligand 3-(2-bromo-4-... 13 34
Aurora kinase A inhibitor AGN-PC-07ZZEH family 2 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
cGMP-specific 3',5'-cyclic phosphodiesterase and Potassium vol... 13 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN5... 6 24
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 46 9
Ephrin type-B receptor 4 ligand SureCN3289519 family 4 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 10
Adenosine kinase inhibitor 5-[3-(3-bromophenyl)propyl]-6-[2-(6... 3 0
Epidermal growth factor receptor ligand pyrido[4,3-d]pyrimidin... 11 0
Nuclear receptor ROR-gamma and 15-hydroxyprostaglandin dehydro... 1 1
Corticotropin-releasing factor receptor 1 ligand 3-(2-bromo-4-... 7 1
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 15 3
Corticotropin-releasing factor receptor 1 ligand 3-(2,4-dibrom... 2 0
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 5 2
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 3
Transient receptor potential cation channel subfamily V member... 4 0
Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... 5 3
Protein kinase C theta type and Protein kinase C delta type in... 9 0
Motilin receptor ligand SureCN2004322 family 2 1
TGF-beta receptor type-2 and Vascular endothelial growth facto... 2 1
Cyclin-dependent kinase 1 and Proto-oncogene tyrosine-protein ... 5 13
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 16 7
Epidermal growth factor receptor ligand Pyrroloquinazoline der... 7 0
Adenosine kinase inhibitor SureCN8248615 family 2 3
Epidermal growth factor receptor ligand AGN-PC-073LJS family 4 0
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 11 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 12 0
Adenosine kinase inhibitor AGN-PC-074DKZ family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00307220 CHEMBL101805 Bioactive AGN-PC-074UAJ
CFAMM00307225 CHEMBL103812 Bioactive AGN-PC-074UD8
CFAMM00307230 CHEMBL102989 Bioactive 5-(3-bromophenyl)-7-[6-[(3S,4R)-3,4-diethoxypyrrolidin-1-yl]pyridazin-3-yl]pyrido[2,3-d]pyrimidin-4-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27063 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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