CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10809
Family Name DNA gyrase subunit B inhibitor N-ethyl-5-[6-methoxy-5-(2-oxo-3H-1,3,4-oxadiazol-5-yl)pyridin-3-yl]-4-[3-(trifluoromethyl)pyrazol-1-yl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00404585 Functional Category Bioactive
Superfamily Potassium voltage-gated channel subfamily H member 2 and Vascular endothelial growth factor receptor 2 Ligand BMS-645737 Superfamily
Class Class 2483

Cousin Family NamesSeedsMembers
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 4 32
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Reverse transcriptase Inhibitor Atevirdine Family 4 55
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07RDWA fa... 1 4
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QJGR family 3 13
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 1 1
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 19 10
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 12 13
MAP kinase-activated protein kinase 2 inhibitor 4-fluoro-N-[4-... 25 1
Mitogen-activated protein kinase 14 inhibitor AGN-PC-075YLX fa... 3 1
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 2 8
Aurora kinase A and Aurora kinase B inhibitor [4-[[7-cyclopent... 6 0
DNA gyrase subunit B inhibitor 5-[2-(ethylcarbamoyl)-4-[3-(tri... 2 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 16 5
Growth hormone secretagogue receptor type 1 ligand SureCN36800... 14 42
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-[5-(diflu... 7 0
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 12 3
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 1 0
Serine/threonine-protein kinase PLK4 inhibitor (3E)-5-methoxy-... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00404585 CHEMBL2059379 Bioactive N-ethyl-5-[6-methoxy-5-(2-oxo-3H-1,3,4-oxadiazol-5-yl)pyridin-3-yl]-4-[3-(trifluoromethyl)pyrazol-1-yl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
CFAMM00404584 CHEMBL2059378 Bioactive N-ethyl-5-[5-(2-oxo-3H-1,3,4-oxadiazol-5-yl)pyridin-3-yl]-4-[3-(trifluoromethyl)pyrazol-1-yl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
CFAMM00404583 CHEMBL2059380 Bioactive N-ethyl-5-[2-methoxy-5-(2-oxo-3H-1,3,4-oxadiazol-5-yl)pyridin-3-yl]-4-[3-(trifluoromethyl)pyrazol-1-yl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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