CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10828
Family Name Calcitonin gene-related peptide type 1 receptor and Cytochrome P450 3A4 ligand N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide family
No. of Seeds 4 No. of Other Members 7
Family Centroid CFAMM00404747 Functional Category Bioactive
Superfamily Calcitonin gene-related peptide type 1 receptor and Cytochrome P450 3A4 Binder Superfamily
Class Class 3332

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 Inhibitor AZD7762 Family 26 90
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 6 3
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-4-m... 1 0
D(2) dopamine receptor and Potassium voltage-gated channel sub... 1 1
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 2 17
Transient receptor potential M8 protein ligand 2-(1-benzothiop... 1 0
Neuropeptide Y receptor type 1 ligand 1-(1-benzothiophen-6-yl)... 1 0
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 7 11
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
5-hydroxytryptamine receptor 1A ligand (3R)-N-(1-adamantyl)-1,... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00404747 CHEMBL2059880 Bioactive N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide
CFAMM00404757 CHEMBL466555 Bioactive N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide
CFAMM00404755 CHEMBL2059906 Bioactive N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-2-oxospiro[1,3-dihydroquinazoline-4,4'-piperidine]-1'-carboxamide
CFAMM00404748 CHEMBL2059881 Bioactive N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-4-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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