CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10834
Family Name Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-aminobutyric acid receptor subunit beta-2 ligand 3-methylbutyl 6-ethyl-4-oxo-1H-quinoline-3-carboxylate family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00318990 Functional Category Bioactive
Superfamily Beta-lactamase and Integrase Binder Superfamily
Class Class 946

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Retinoic acid receptor alpha Ligand LG100268 Family 2 33
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Metabotropic glutamate receptor 5 Ligand 6-phenylethynyl-nicot... 2 26
5-hydroxytryptamine receptor 3A Ligand 3alpha-(1'-methyl-2'-in... 2 17
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 10 4
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 3 28
Cellular tumor antigen p53 and Lethal(3)malignant brain tumor-... 1 6
Retinoic acid receptor RXR-alpha ligand 6-[(3-butoxy-5,5,8,8-t... 2 2
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 4
Cytosolic phospholipase A2 inhibitor AGN-PC-00BH8R family 6 13
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 1 3
Cyclin-dependent kinase 2 and Vascular endothelial growth fact... 1 1
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
Cysteinyl leukotriene receptor 1 ligand 2-[2-[5-[[3-[(E)-2-(6,... 1 8
Histamine H1 receptor and Histamine H2 receptor ligand SureCN6... 1 3
Histamine H1 receptor and Histamine H2 receptor ligand SureCN5... 3 6
Methionine aminopeptidase 1 inhibitor ethyl 4-[4-(2-pyridin-2-... 2 3
Glycine receptor subunit alpha-1 ligand [(1R,5R)-8-azabicyclo[... 2 10
Transmembrane prolyl 4-hydroxylase inhibitor 2,2'-Bipyridine-5... 1 1
2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium-8-carboxylate N... 2 0


External ID

Functional Category

Molecule Name

CFAMM00404791 CHEMBL419391 Bioactive AC1MIMAE

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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