CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10840
Family Name Pol polyprotein inhibitor L-689,502 family
No. of Seeds 17 No. of Other Members 2
Family Centroid CFAMM00404884 Functional Category Bioactive
Superfamily Pol polyprotein and Matrix metalloproteinase-9 Binder Superfamily
Class Class 3076

Cousin Family NamesSeedsMembers
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Plasmepsin-2 Inhibitor KNI-10079 Family 19 8
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 40 29
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-5-benzyl-3-... 2 3
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 11 8
Pol polyprotein inhibitor 180968-31-4 family 8 13
Pol polyprotein inhibitor benzyl N-[(2S,3R)-1-[[(2S,3R,4R)-4-(... 5 26
Pol polyprotein inhibitor AC1L9R8S family 5 4
Pol polyprotein inhibitor (2S)-4-benzyl-1-[(2S,4R)-4-benzyl-2-... 10 4
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 4
Pol polyprotein inhibitor (2R,3R,4R,5R)-2,3,4-trihydroxy-N,N'-... 3 3
E3 ubiquitin-protein ligase XIAP inhibitor N-METHYLALANYL-3-ME... 3 14
Pol polyprotein inhibitor MK-944a family 6 1
Renin inhibitor N-[(2S,4S,5S,7S)-7-[2-(1-acetylpiperidin-4-yl)... 2 1
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Pol polyprotein inhibitor (2R)-2-benzyl-5-[(3S,5R)-3-benzyl-5-... 11 5
Pol polyprotein inhibitor 3-[[(3S,5R)-5-benzyl-1-[(2S,4R)-4-be... 4 0
Pol polyprotein inhibitor AC1LADII family 12 1
Pol polyprotein inhibitor SureCN3530080 family 3 8
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-5-benzyl-3-... 3 0
Pol polyprotein inhibitor SDZ PRI 053 family 8 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 4
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5S)-3-hydroxy-5... 4 12
Pol polyprotein inhibitor AC1NS2O6 family 3 0
Pol polyprotein inhibitor AC1L9R8M family 4 1
Pol polyprotein inhibitor (2R)-5-[(3S,5R)-3,5-dibenzyl-2-oxopy... 3 0
Pol polyprotein inhibitor AC1L9XVT family 4 0
Pol polyprotein inhibitor (2R,4S)-2-benzyl-5-[2-(tert-butylsul... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00404892 CHEMBL295442 Bioactive AC1L9RCQ
CFAMM00404885 CHEMBL291203 Bioactive AC1L9RCL
CFAMM00404898 CHEMBL46274 Bioactive AC1L9RCS
CFAMM00404891 CHEMBL44578 Bioactive AC1L9RCN
CFAMM00404884 CHEMBL2062158 Bioactive L-689,502
CFAMM00404890 CHEMBL45457 Bioactive tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-6-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-1-[4-(2-morpholin-4-ylethoxy)phenyl]-6-oxohexan-2-yl]carbamate
CFAMM00404896 CHEMBL47712 Bioactive AC1L9RCP
CFAMM00404889 CHEMBL45451 Bioactive tert-butyl N-[(2S,3S,5R)-3-hydroxy-6-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-6-oxo-1-phenyl-5-[(4-phenylmethoxyphenyl)methyl]hexan-2-yl]carbamate
CFAMM00404902 CHEMBL297673 Bioactive AC1L9RCU
CFAMM00404895 CHEMBL295549 Bioactive AC1L9RCT
CFAMM00404901 CHEMBL295414 Bioactive 2-[4-[(4S,5S)-4-hydroxy-2-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl]-5-[(2-methylpropan-2-yl)oxycarbonylamino]-6-phenylhexyl]phenoxy]acetic acid
CFAMM00404894 CHEMBL295482 Bioactive AC1L9RCO
CFAMM00404887 CHEMBL45474 Bioactive tert-butyl N-[(2S,3S,5R)-3-hydroxy-6-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-[[4-(3-morpholin-4-ylpropoxy)phenyl]methyl]-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00404900 CHEMBL295609 Bioactive AC1L9RCM
CFAMM00404893 CHEMBL416082 Bioactive AC1L9RCR
CFAMM00404886 CHEMBL295013 Bioactive tert-butyl N-[(2S,3S,5R)-3-hydroxy-6-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-1-[4-(2-morpholin-4-ylethoxy)phenyl]-5-[[4-(2-morpholin-4-ylethoxy)phenyl]methyl]-6-oxohexan-2-yl]carbamate
CFAMM00404899 CHEMBL46062 Bioactive tert-butyl N-[(2S,3S,5R)-5-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3-hydroxy-6-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-6-oxo-1-phenylhexan-2-yl]carbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48705 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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