CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10853
Family Name 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine receptor 2C ligand AGN-PC-0762CG family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00304962 Functional Category Bioactive
Superfamily Oxytocin receptor and Vasopressin V1a receptor Ligand 1'-tosylspiro[indene-1,4'-piperidine] Superfamily
Class Class 578

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Muscarinic acetylcholine receptor M5 Ligand Metixene Family 5 24
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor Liga... 3 29
5-hydroxytryptamine receptor 5A and 5-hydroxytryptamine recept... 12 20
Potassium voltage-gated channel subfamily H member 2 Ligand 4-... 4 26
Alpha-2A adrenergic receptor Ligand SK&F-29661 Family 3 42
D(2) dopamine receptor Ligand 4-[3-(methylsulfonyl)phenyl]-1-p... 2 2
Oxytocin receptor and Vasopressin V1a receptor Ligand 1'-tosyl... 1 7
Squalene synthase Inhibitor Zwitterionic Sulfobetaine Derivati... 2 20
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (1S,5... 2 4
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 34
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 2 11
C-C chemokine receptor type 5 ligand methyl N-[1-[(3S)-4-[benz... 3 18
Histamine H3 receptor ligand 2-[4-[4-[2-[(2R)-2-methylpyrrolid... 4 11
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 6 4
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 1
Sigma non-opioid intracellular receptor 1 ligand 1-benzyl-4-[(... 3 2
Sigma non-opioid intracellular receptor 1 ligand 4-benzyl-1-[(... 1 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 7
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 4 0
C-C chemokine receptor type 5 ligand AC1L9YN4 family 2 33
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 0
Histamine H3 receptor ligand N,N-diethyl-4-[4-[2-[(2R)-2-methy... 4 0
Neuropeptide Y receptor type 5 ligand AGN-PC-0A7RNK family 2 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor N-... 1 2
Lanosterol synthase inhibitor (E)-but-2-enedioic acid;N-[4-[5-... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00404963 CHEMBL206307 Bioactive 2-[4-[2-(2,4-difluorophenyl)ethyl]piperidin-1-yl]sulfonylbenzonitrile
CFAMM00404972 CHEMBL207850 Bioactive 1-[2-(2,4-difluorophenyl)ethyl]-4-(4-fluorophenyl)sulfonylpiperazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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