CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1086
Family Name Coagulation factor X and Cationic trypsin inhibitor AC1L1JML family
No. of Seeds 11 No. of Other Members 32
Family Centroid CFAMM00319229 Functional Category Bioactive
Superfamily Integrin beta-3 Inhibitor SB-208651 Superfamily
Class Class 2096

Cousin Family NamesSeedsMembers
DNA Binder Procarbazine Family 8 358
Neuropeptide Y receptor type 1 Ligand BIBO3304 Family 4 69
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Prothrombin Inhibitor LB30812 Family 12 36
Poly(ADP-ribose) glycohydrolase Inhibitor N-bis-(3-phenyl-prop... 3 7
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibit... 5 23
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Chymotrypsin-like elastase family member 2A and Chymotrypsinog... 2 18
Coagulation factor X and Cationic trypsin inhibitor methyl (3Z... 2 7
Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-6-[[2-(4... 2 11
Coagulation factor X and Trypsin-1 inhibitor 3-carbamimidoyl-N... 1 1
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7301018... 4 3
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7961093... 1 0
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-0757VU... 13 39
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7307400... 1 3
Coagulation factor X and Coagulation factor VII inhibitor AGN-... 1 2
Tryptase alpha/beta-1 inhibitor 4-[[(4-carbamimidoylbenzoyl)am... 1 2


External ID

Functional Category

Molecule Name

CFAMM00319268 CHEMBL45106 Bioactive methyl (2R,3R)-3-[[4-[3-(aminomethyl)phenyl]benzoyl]amino]-2-[(3-carbamimidoylphenyl)methyl]-4-cyclohexylbutanoate
CFAMM00319261 CHEMBL44050 Bioactive methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(3-carbamoylphenyl)benzoyl]amino]butanoate
CFAMM00319260 CHEMBL48610 Bioactive methyl (2R,3R)-3-[[4-[3-(aminomethyl)phenyl]benzoyl]amino]-2-[(3-carbamimidoylphenyl)methyl]pentanoate
CFAMM00319266 CHEMBL417714 Bioactive methyl (E,2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-5-phenyl-3-[(4-phenylbenzoyl)amino]pent-4-enoate
CFAMM00319259 CHEMBL44831 Bioactive methyl (2R,3R)-3-[[4-[3-(aminomethyl)phenyl]benzoyl]amino]-2-[(3-carbamimidoylphenyl)methyl]-5-methylhexanoate
CFAMM00319272 CHEMBL44177 Bioactive methyl (2R,3R)-3-[[4-[3-(aminomethyl)phenyl]benzoyl]amino]-2-[(3-carbamimidoylphenyl)methyl]-4-methylpentanoate
CFAMM00319252 CHEMBL48046 Bioactive rpr128515
CFAMM00319271 CHEMBL45267 Bioactive methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(4-carbamoylphenyl)benzoyl]amino]butanoate
CFAMM00319270 CHEMBL45000 Bioactive methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[(4-phenylbenzoyl)amino]butanoate
CFAMM00319229 CHEMBL110419 Bioactive AC1L1JML
CFAMM00319269 CHEMBL47704 Bioactive methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-[3-[(dimethylamino)methyl]phenyl]benzoyl]amino]butanoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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