CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10863
Family Name Aurora kinase A and Aurora kinase B inhibitor 4-amino-N-[4-(thiophen-3-ylcarbamoylamino)phenyl]pyrrolo[2,1-f][1,2,4]triazine-5-carboxamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00112707 Functional Category Bioactive
Superfamily Omega 1 Benzodiazepine receptor Ligand Indiplon Superfamily
Class Class 689

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Indiplon Family 4 25
Aurora kinase A Inhibitor ABT-348 Family 20 49
Mitogen-activated protein kinase 11 and Mitogen-activated prot... 10 31
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 16
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 13
Sphingosine 1-phosphate receptor 1 ligand SureCN3029336 family 4 8
Orexin receptor type 2 and Orexin receptor type 1 ligand [(7R)... 10 10
Orexin receptor type 2 and Orexin receptor type 1 ligand SureC... 2 3
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-07ZE3... 6 1
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Mitogen-activated protein kinase 14 inhibitor AGN-PC-069K8I fa... 12 3
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 0
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... 17 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 13 3
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 11 0
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 6 1
Mitogen-activated protein kinase 14 inhibitor ethyl N-[4-[5-(m... 5 2
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... 2 2
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Histone deacetylase 1 inhibitor N-hydroxy-5-[1-[2-[(4-imidazol... 1 0
Tyrosine-protein kinase SYK and Potassium voltage-gated channe... 1 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Probable G-protein coupled receptor 142 ligand 5-butyl-N-[(3-m... 4 0
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Mitogen-activated protein kinase 14 inhibitor AGN-PC-006UPD fa... 1 1
Casein kinase II subunit alpha inhibitor CHEMBL401945 family 12 1
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Platelet-activating factor receptor ligand 1,8-dimethyl-5-[4-(... 1 0
Adenosine receptor A1 and Adenosine receptor A2a ligand AGN-PC... 1 0
MAP kinase-activated protein kinase 2 and Cyclin-dependent kin... 1 0
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-07C04Y... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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