Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.
CFAM Family ID CFFBM1087 Family Name Pol polyprotein inhibitor 2-[(2R,3S)-3-[[(2R)-3-(benzenesulfinyl)-2-(methanesulfonamido)propanoyl]amino]-2-hydroxy-4-phenylbutyl]-N-tert-butylbenzamide family No. of Seeds 15
No. of Other Members 15
Family Centroid CFAMM00319297 Functional Category Bioactive
Superfamily Pol polyprotein Binder Superfamily 6 Class Class 2411
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAMM00319279 CHEMBL11143 Bioactive
N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-[[(2R)-2-(methanesulfonamido)-3-naphthalen-1-ylsulfonylpropanoyl]amino]-4-phenylbutyl]benzamide CFAMM00319298 CHEMBL11116 Bioactive
N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-[[(2R)-2-(methanesulfonamido)-3-naphthalen-1-ylsulfinylpropanoyl]amino]-4-phenylbutyl]benzamide CFAMM00319291 CHEMBL11426 Bioactive
N-tert-butyl-2-[(2R,3S)-3-[[(2R)-3-(4-fluorophenyl)sulfanyl-2-(methanesulfonamido)propanoyl]amino]-2-hydroxy-4-phenylbutyl]benzamide CFAMM00319297 CHEMBL11137 Bioactive
2-[(2R,3S)-3-[[(2R)-3-(benzenesulfinyl)-2-(methanesulfonamido)propanoyl]amino]-2-hydroxy-4-phenylbutyl]-N-tert-butylbenzamide CFAMM00319290 CHEMBL276656 Bioactive
N-tert-butyl-2-[(2R,3S)-3-[[(2R)-3-(4-fluorophenyl)sulfonyl-2-(methanesulfonamido)propanoyl]amino]-2-hydroxy-4-phenylbutyl]benzamide CFAMM00319277 CHEMBL267092 Bioactive
2-[(2R,3S)-3-[[(2R)-3-(benzenesulfonyl)-2-(methanesulfonamido)propanoyl]amino]-2-hydroxy-4-phenylbutyl]-N-tert-butylbenzamide CFAMM00319296 CHEMBL273368 Bioactive
N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-[[(2R)-2-(methanesulfonamido)-3-naphthalen-2-ylsulfinylpropanoyl]amino]-4-phenylbutyl]benzamide CFAMM00319276 CHEMBL274186 Bioactive
N-tert-butyl-2-[(2R,3S)-3-[[(2R)-3-(4-chlorophenyl)sulfonyl-2-(methanesulfonamido)propanoyl]amino]-2-hydroxy-4-phenylbutyl]benzamide CFAMM00319275 CHEMBL418528 Bioactive
N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-[[(2R)-2-(methanesulfonamido)-3-[4-(trifluoromethyl)phenyl]sulfinylpropanoyl]amino]-4-phenylbutyl]benzamide CFAMM00319288 CHEMBL11421 Bioactive
N-tert-butyl-2-[(2R,3S)-3-[[(2R)-3-(4-fluorophenyl)sulfinyl-2-(methanesulfonamido)propanoyl]amino]-2-hydroxy-4-phenylbutyl]benzamide CFAMM00319301 CHEMBL406991 Bioactive
N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-[[(2R)-2-(methanesulfonamido)-3-naphthalen-1-ylsulfanylpropanoyl]amino]-4-phenylbutyl]benzamide CFAMM00319294 CHEMBL277985 Bioactive
D-Cysteine Analog 15c CFAMM00319274 CHEMBL276379 Bioactive
2-[(2R,3S)-3-[[(2R)-2-acetamido-3-naphthalen-2-ylsulfonylpropanoyl]amino]-2-hydroxy-4-phenylbutyl]-N-tert-butylbenzamide CFAMM00319300 CHEMBL11050 Bioactive
N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-[[(2R)-2-(methanesulfonamido)-3-naphthalen-2-ylsulfanylpropanoyl]amino]-4-phenylbutyl]benzamide CFAMM00319293 CHEMBL274569 Bioactive
N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-[[(2R)-2-(methanesulfonamido)-3-[4-(trifluoromethyl)phenyl]sulfonylpropanoyl]amino]-4-phenylbutyl]benzamide
CFAM Mol ID
External ID
Functional Category
Molecule Name
Statistics of CFAM Database
490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
How to cite our database
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
Last update by
2014.08.29
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Chen Yuzong Deputy
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