CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10879
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform inhibitor 2-[(5-fluoro-4-phenyl-1,3-benzoxazol-2-yl)methyl]-6-morpholin-4-yl-1H-pyrimidin-4-one family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00405135 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Binder Superfamily 4
Class Class 2433

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 2 and C-C motif chemokine 2 Ligand... 3 52
Chymase Inhibitor Y-40613 Family 11 56
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Arachidonate 5-lipoxygenase Inhibitor 5-methyl-n-phenylbenzo[d... 5 13
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
Somatostatin receptor type 5 and Potassium voltage-gated chann... 2 21
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
5-hydroxytryptamine receptor 3A ligand 2-[(3S)-3-ethylmorpholi... 10 18
5-hydroxytryptamine receptor 3A and Potassium voltage-gated ch... 1 0
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 4 1
Cannabinoid receptor 2 ligand [4-(5-tert-butyl-1,3-benzoxazol-... 4 1
Melanin-concentrating hormone receptor 1 ligand N-[3-(2-aminoq... 4 1
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 1 0
Coagulation factor X and Plasma kallikrein inhibitor (2R)-N-[2... 1 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
Cathepsin S and Cathepsin L1 inhibitor (2S)-2-(1,3-benzoxazol-... 1 9
Somatostatin receptor type 5 ligand SureCN3572493 family 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00405135 CHEMBL2064417 Bioactive 2-[(5-fluoro-4-phenyl-1,3-benzoxazol-2-yl)methyl]-6-morpholin-4-yl-1H-pyrimidin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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