CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10880
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform inhibitor N-[6-[5-(sulfamoylmethyl)pyridin-3-yl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00405137 Functional Category Bioactive
Superfamily TGF-beta receptor type-1 and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Binder Superfamily
Class Class 195

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
HER Inhibitor AC480 Family 4 67
Tyrosine-protein kinase JAK2 Inhibitor INCB18424 Family 3 130
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 13 100
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 18
Adenosine receptor A3 ligand AGN-PC-07N4XX family 6 10
Adenosine receptor A3 ligand AGN-PC-07N4XY family 2 2
Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-... 5 1
Prothrombin and Histone-lysine N-methyltransferase 2A inhibito... 1 7
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 6 1
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Survival motor neuron protein inhibitor CHEMBL1583999 family 1 3
5-hydroxytryptamine receptor 6 ligand 3-(benzenesulfonyl)-N,5-... 4 1
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07CBUP family 2 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 2 3
Aurora kinase A and Cyclin-dependent kinase 1 inhibitor N-[4-[... 12 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 11
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
Casein kinase II subunit alpha inhibitor AGN-PC-0766PM family 4 0
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 11 3
Vascular endothelial growth factor receptor 1 and Vascular end... 4 0
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 15
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 1
Casein kinase II subunit alpha and Homeodomain-interacting pro... 5 0
Casein kinase II subunit alpha inhibitor N-[5-[[3-cyano-7-(cyc... 3 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 16 5
Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-(7-aminop... 1 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 1
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
Serine/threonine-protein kinase TBK1 inhibitor N-[3-[[5-cyclop... 3 0
Fatty-acid amide hydrolase 1 inhibitor 4-(3-phenyl-1,2,4-thiad... 2 1
Tyrosine-protein kinase JAK2 inhibitor N,N-dimethyl-4-[[8-(4-m... 2 1
Tyrosine-protein kinase JAK2 inhibitor N-(3-methylphenyl)-5-(3... 2 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Glucocorticoid receptor ligand 3-[1-(4-fluorophenyl)indazol-5-... 16 10
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
Fatty-acid amide hydrolase 1 and Liver carboxylesterase 1 inhi... 1 0
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-b]pyridazine d... 2 1
Corticotropin-releasing factor receptor 1 ligand 3-[6-(dimethy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00405137 CHEMBL2064501 Bioactive N-[6-[5-(sulfamoylmethyl)pyridin-3-yl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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