CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10893
Family Name Dipeptidyl peptidase 4 inhibitor 2-cyanopyrrolidine 21e family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00405205 Functional Category Bioactive
Superfamily Histamine H3 receptor and Dipeptidyl peptidase 4 Binder Superfamily
Class Class 412

Cousin Family NamesSeedsMembers
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Histamine H3 receptor ligand SureCN4316818 family 11 24
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 4
Histamine H3 receptor ligand SureCN4319687 family 8 15
Growth hormone secretagogue receptor type 1 ligand 2-amino-2-m... 1 0
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6S... 1 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 12
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 4
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,5R)-5-[(7-bromo-1... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor 2-... 4 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor 2-... 3 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor 2-... 1 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 7 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 3
Scytalone dehydratase inhibitor (2R)-2-cyano-N-[(2R)-1-(2,3-di... 15 0
Dipeptidyl peptidase 4 inhibitor 2-cyanopyrrolidine 21b family 1 0
72 kDa type IV collagenase inhibitor AGN-PC-03EJ2S family 8 5
Dipeptidyl peptidase 4 inhibitor 3-[[2-[(2S,4S)-2-cyano-4-fluo... 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00405206 CHEMBL382167 Bioactive 2-cyanopyrrolidine 21h
CFAMM00405205 CHEMBL380894 Bioactive 2-cyanopyrrolidine 21e
CFAMM00405211 CHEMBL210275 Bioactive 2-cyanopyrrolidine 21aa
CFAMM00405210 CHEMBL207650 Bioactive 2-cyanopyrrolidine 21g
CFAMM00405209 CHEMBL206573 Bioactive 2-cyanopyrrolidine 21a
CFAMM00405208 CHEMBL379812 Bioactive (2S)-1-[(2S,5R)-5-(naphthalen-2-yloxymethyl)pyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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