CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10905
Family Name Neuropeptide Y receptor type 5 and Cytochrome P450 1A2 ligand 6-ethylsulfonyl-2-(3-phenylphenyl)-1H-benzimidazole family
No. of Seeds 8 No. of Other Members 19
Family Centroid CFAMM00360977 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 and Cytochrome P450 1A2 Binder Superfamily
Class Class 2756

Cousin Family NamesSeedsMembers
Tryptase Inhibitor Babim Family 12 90
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 1 9
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(4-e... 2 5
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Pol polyprotein and Reverse transcriptase/RNaseH inhibitor AC1... 6 11
Growth hormone secretagogue receptor type 1 and Dihydrofolate ... 3 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Cannabinoid receptor 2 ligand 2-tert-butyl-5-ethylsulfonyl-1-(... 28 32
Fatty-acid amide hydrolase 1 inhibitor 5-[5-(4-chlorophenyl)su... 2 4
Mitogen-activated protein kinase 14 inhibitor 6-[5-(2,4-difluo... 9 3
Cyclin-dependent kinase 1 inhibitor 4-[[4-(3H-benzimidazol-5-y... 1 0
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 1
Neuropeptide Y receptor type 5 and Cytochrome P450 1A2 ligand ... 2 3
Neuropeptide Y receptor type 5 ligand 2-(3-phenylpiperidin-1-y... 6 2
Neuropeptide Y receptor type 5 ligand 2-phenyl-4-(6-propylsulf... 12 5
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 3 4
Urokinase plasminogen activator surface receptor ligand 3-(1H-... 4 0
Neuropeptide Y receptor type 5 ligand 2-(2,2-difluoro-2-phenyl... 2 2
Neuropeptide Y receptor type 5 ligand 6-ethylsulfonyl-2-(4-phe... 4 4
Neuropeptide Y receptor type 5 ligand (6-ethylsulfonyl-1H-benz... 1 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor AG... 3 1
Cannabinoid receptor 2 ligand 4-[[2-tert-butyl-1-(cyclohexylme... 2 0
Cannabinoid receptor 2 ligand 4-[2-tert-butyl-1-(oxan-4-ylmeth... 5 0
Mitogen-activated protein kinase 14 inhibitor 6-[2-[2-chloro-6... 2 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 1 0
Cannabinoid receptor 2 ligand 5-chloro-6-[(4-chlorophenyl)meth... 1 0
5-hydroxytryptamine receptor 2B ligand SureCN1299053 family 1 1
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00405295 CHEMBL2070151 Bioactive 2-(4-chloro-3-phenylphenyl)-6-ethylsulfonyl-1H-benzimidazole
CFAMM00405300 CHEMBL2070140 Bioactive 2-(3-phenylphenyl)-6-propylsulfonyl-1H-benzimidazole
CFAMM00405311 CHEMBL2069316 Bioactive 6-ethylsulfonyl-2-(4-methyl-3-phenylphenyl)-1H-benzimidazole
CFAMM00405304 CHEMBL2070147 Bioactive 6-ethylsulfonyl-2-(2-fluoro-5-phenylphenyl)-1H-benzimidazole
CFAMM00405310 CHEMBL2070148 Bioactive 6-ethylsulfonyl-2-(4-fluoro-3-phenylphenyl)-1H-benzimidazole
CFAMM00405303 CHEMBL2070146 Bioactive 6-ethylsulfonyl-2-(2-fluoro-3-phenylphenyl)-1H-benzimidazole
CFAMM00405309 CHEMBL2070141 Bioactive 2-(4-phenylphenyl)-6-propylsulfonyl-1H-benzimidazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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