CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10910
Family Name Metabotropic glutamate receptor 5 and Potassium voltage-gated channel subfamily H member 2 ligand 4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(4-fluorophenyl)pyrrolidin-2-one family
No. of Seeds 2 No. of Other Members 35
Family Centroid CFAMM00405365 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 Binder Superfamily 5
Class Class 1234

Cousin Family NamesSeedsMembers
Prelamin-A/C and Putative fructose-1,6-bisphosphate aldolase i... 1 7
Cellular tumor antigen p53 inhibitor CHEMBL1398842 family 1 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor N-... 1 6
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 16
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 3-[3-... 1 1
Metabotropic glutamate receptor 5 ligand azepan-1-yl-[3-[3-(3-... 1 11
Metabotropic glutamate receptor 5 ligand [(3S)-3-bicyclo[2.2.1... 4 5
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 2 0
Metabotropic glutamate receptor 5 ligand 5-[(7S)-3-tert-butyl-... 1 0
Dipeptidyl peptidase 4 inhibitor (2R)-1-(2-fluorophenyl)-4-[(2... 1 2


External ID

Functional Category

Molecule Name

CFAMM00405367 CHEMBL2069398 Bioactive 1-(4-fluorophenyl)-4-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
CFAMM00405365 CHEMBL2069397 Bioactive 4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(4-fluorophenyl)pyrrolidin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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