CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10926
Family Name Neuropeptide Y receptor type 5 ligand 1-phenyl-5-[6-(2,2,2-trifluoroethylsulfonyl)-1H-benzimidazol-2-yl]pyridin-2-one family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00405443 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 and Cytochrome P450 1A2 Binder Superfamily
Class Class 2756

Cousin Family NamesSeedsMembers
Cannabinoid receptor 2 ligand 2-tert-butyl-5-ethylsulfonyl-1-(... 28 32
C-C chemokine receptor type 2 ligand N-[(1S,2R,4R)-2-(benzenes... 7 9
Neuropeptide Y receptor type 5 ligand 2-(3-phenylpiperidin-1-y... 6 2
Neuropeptide Y receptor type 5 ligand 2-phenyl-4-(6-propylsulf... 12 5


External ID

Functional Category

Molecule Name

CFAMM00405443 CHEMBL2070161 Bioactive 1-phenyl-5-[6-(2,2,2-trifluoroethylsulfonyl)-1H-benzimidazol-2-yl]pyridin-2-one
CFAMM00405442 CHEMBL2070160 Bioactive 1-phenyl-5-[6-(trifluoromethylsulfonyl)-1H-benzimidazol-2-yl]pyridin-2-one
CFAMM00405441 CHEMBL2070158 Bioactive 1-phenyl-5-(6-propylsulfonyl-1H-benzimidazol-2-yl)pyridin-2-one
CFAMM00405440 CHEMBL2070159 Bioactive 5-(6-tert-butylsulfonyl-1H-benzimidazol-2-yl)-1-phenylpyridin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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