CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10927
Family Name S-methyl-5'-thioadenosine phosphorylase inhibitor 2-[[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methylamino]methyl]-3-methylsulfanylpropan-1-ol family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00405447 Functional Category Bioactive
Superfamily S-methyl-5'-thioadenosine phosphorylase and 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Binder Superfamily
Class Class 3353

Cousin Family NamesSeedsMembers
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Adenosine receptor A1 Ligand SLV320 Family 6 79
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... 5 16
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase inh... 17 17
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase inh... 7 6
S-methyl-5'-thioadenosine phosphorylase inhibitor SureCN997478... 8 0
S-methyl-5'-thioadenosine phosphorylase inhibitor 1-[(4-amino-... 7 1
Tyrosine-protein kinase JAK1 and Non-receptor tyrosine-protein... 7 0
Adenosine receptor A3 ligand (2R,3R,4S)-2-[2-chloro-6-[(3-fluo... 6 7
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 16 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00405446 CHEMBL2070308 Bioactive (2R)-2-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methylamino]-3-methylsulfanylpropan-1-ol
CFAMM00405445 CHEMBL2070311 Bioactive (2R,3S)-2-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methylamino]-4-methylsulfanylbutane-1,3-diol
CFAMM00405447 CHEMBL2070310 Bioactive 2-[[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methylamino]methyl]-3-methylsulfanylpropan-1-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27298 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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