CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1093
Family Name B2 bradykinin receptor ligand AGN-PC-074WA4 family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00319388 Functional Category Bioactive
Superfamily Beta-lactamase and D(2) dopamine receptor Binder Superfamily
Class Class 220

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Mu-type opioid receptor ligand opiate Remifentanil Family 10 24
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Alpha adrenergic receptor Ligand Droperidol Family 20 244
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Motilin receptor Ligand GSK962040 Family 30 457
Nociceptin receptor Ligand J-113397 Family 3 14
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 19 88
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Induced myeloid leukemia cell differentiation protein Mcl-1 an... 2 7
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 3 3
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 10
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 5 2
Cannabinoid receptor 2 ligand SureCN738026 family 5 68
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 5 14
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 4 6
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 3
Calcitonin gene-related peptide type 1 receptor and Dual speci... 8 4
Substance-P receptor ligand (2S,4S)-2-N-[3-(diethylamino)propy... 2 7
5-hydroxytryptamine receptor 1A ligand SureCN4244417 family 10 1
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S)-4-anilinopyrr... 2 13
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 11 3
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 2 17
Nociceptin receptor ligand 2-[3-[1-[(1R)-1,2-dihydroacenaphthy... 2 0
Melanin-concentrating hormone receptor 1 ligand 3-chloro-5-[4-... 2 0
Translocator protein inhibitor CHEMBL2332254 family 6 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 1
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Mu-type opioid receptor and Nociceptin receptor ligand SureCN8... 7 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 1
Nociceptin receptor and Mu-type opioid receptor ligand spiropi... 1 0
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 7 1
C5a anaphylatoxin chemotactic receptor 1 ligand SureCN12047568... 1 1
Aldose reductase inhibitor (4R)-6-fluoro-3-methylspiro[1H-quin... 4 16
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 2 0
Substance-P receptor ligand (2S)-2-N-[2-[(3,5-dimethylphenyl)m... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00319392 CHEMBL1762372 Bioactive SureCN5108502
CFAMM00319388 CHEMBL110652 Bioactive AGN-PC-074WA4

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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