CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10931
Family Name LIM domain kinase 2 and LIM domain kinase 1 inhibitor N-[5-[6-(2,6-dichloro-4-methoxyphenyl)-2-pyrazin-2-ylpyrimidin-4-yl]-1,3-thiazol-2-yl]acetamide family
No. of Seeds 1 No. of Other Members 22
Family Centroid CFAMM00405481 Functional Category Bioactive
Superfamily cAMP and LIM domain kinase 2 Binder Superfamily
Class Class 834

Cousin Family NamesSeedsMembers
Rho-associated protein kinase 2 inhibitor SureCN13457044 family 1 17
Aurora kinase A inhibitor SureCN208325 family 1 5
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 7 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 13 1
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 2 6
Adenosine receptor A2a and Adenosine receptor A1 ligand 2-(3-c... 3 3


External ID

Functional Category

Molecule Name

CFAMM00405481 CHEMBL2070619 Bioactive N-[5-[6-(2,6-dichloro-4-methoxyphenyl)-2-pyrazin-2-ylpyrimidin-4-yl]-1,3-thiazol-2-yl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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