CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1094
Family Name Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-1-N-[2-(methoxymethyl)phenyl]pyrrolidine-1,2-dicarboxamide family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00319393 Functional Category Bioactive
Superfamily Substance-P receptor and Vasopressin V2 receptor Binder Superfamily 2
Class Class 1500

Cousin Family NamesSeedsMembers
Cholecystokinin receptor type A Ligand Gi 181771 Family 3 18
Intedanib family 7 54
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 2 2
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 6 3
Cathepsin S inhibitor methyl 2-amino-4-[[(2S)-3-cyclohexyl-1-[... 2 3
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 5 2
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[1-[2-[4-[(2... 2 8
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 2 17
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Glycogen phosphorylase, liver form inhibitor SureCN5195475 family 9 5
Glycogen phosphorylase, liver form inhibitor SureCN5419308 family 3 0
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
Vasopressin V2 receptor ligand SureCN4206215 family 1 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 1 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00319395 CHEMBL110656 Bioactive (2S)-2-N-[(2S)-1-[benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-1-N-[2-(hydroxymethyl)phenyl]pyrrolidine-1,2-dicarboxamide
CFAMM00319394 CHEMBL325312 Bioactive methyl 2-[[(2S)-2-[[(2S)-1-[benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]amino]benzoate
CFAMM00319393 CHEMBL111295 Bioactive (2S)-2-N-[(2S)-1-[benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-1-N-[2-(methoxymethyl)phenyl]pyrrolidine-1,2-dicarboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46113 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543