CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10963
Family Name Integrin alpha-4 and Integrin beta-7 inhibitor (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-(5-ethoxy-2-methyl-3-oxopyridazin-4-yl)phenyl]propanoic acid family
No. of Seeds 9 No. of Other Members 27
Family Centroid CFAMM00405727 Functional Category Bioactive
Superfamily Integrin alpha-4 and Integrin beta-7 Binder Superfamily
Class Class 2652

Cousin Family NamesSeedsMembers
Integrin beta-1 Inhibitor R411 Family 33 44
Integrin alpha-4 Inhibitor Firategrast Family 3 93
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibit... 5 23
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 3 18
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(2,6-di... 2 4
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[1-[2-(... 12 2
Integrin alpha-4 and Integrin beta-7 inhibitor (2S)-2-[(2,6-di... 2 0
Integrin alpha-4 and Integrin beta-7 inhibitor (2S)-3-[4-[5-(1... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00405727 CHEMBL377389 Bioactive (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-(5-ethoxy-2-methyl-3-oxopyridazin-4-yl)phenyl]propanoic acid
CFAMM00405706 CHEMBL207864 Bioactive (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-(2-methyl-5-morpholin-4-yl-3-oxopyridazin-4-yl)phenyl]propanoic acid
CFAMM00405712 CHEMBL208013 Bioactive SureCN6028808
CFAMM00405725 CHEMBL273183 Bioactive (2S)-3-[4-[5-(4-carbamoylphenyl)-2-methyl-3-oxopyridazin-4-yl]phenyl]-2-[(2,6-dichlorobenzoyl)amino]propanoic acid
CFAMM00405711 CHEMBL380217 Bioactive SureCN6028725
CFAMM00405724 CHEMBL208644 Bioactive (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-[5-methoxy-2-(2-morpholin-4-ylethyl)-3-oxopyridazin-4-yl]phenyl]propanoic acid
CFAMM00405710 CHEMBL207432 Bioactive (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-[2-methyl-5-(2-morpholin-4-ylethoxy)-3-oxopyridazin-4-yl]phenyl]propanoic acid
CFAMM00405703 CHEMBL379839 Bioactive (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-[5-(2-hydroxyethoxy)-2-methyl-3-oxopyridazin-4-yl]phenyl]propanoic acid
CFAMM00405722 CHEMBL208950 Bioactive SureCN8280388

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44781 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543