CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10966
Family Name Focal adhesion kinase 1 inhibitor AGN-PC-00AVK6 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00405746 Functional Category Bioactive
Superfamily Adenosine kinase and Tubulin beta-4A chain Binder Superfamily
Class Class 1144

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
Tyrosine-protein kinase SYK Inhibitor R788 Family 3 7
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-00EQPZ fa... 3 4
Tyrosine-protein kinase Lck inhibitor AGN-PC-073GX8 family 12 1
Glycogen synthase kinase-3 alpha and Casein kinase II subunit ... 1 16
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 10
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Dihydrofolate reductase inhibitor AC1L9XPA family 6 5
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Cellular tumor antigen p53 and Lysosomal alpha-glucosidase inh... 1 6
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 10 4
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 5 7
Adenosine kinase inhibitor (2R,3R,4R)-2-[4-(2,3-dihydro-1,4-be... 5 2
ALK tyrosine kinase receptor and Insulin-like growth factor 1 ... 1 4
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 7 16
Mitogen-activated protein kinase kinase kinase 11 and Leucine-... 1 2
Mast/stem cell growth factor receptor Kit and Serine/threonine... 11 29
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 4 3
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 2 2
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Tubulin beta-4A chain and Tubulin beta-2B chain inhibitor AGN-... 1 0
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 8
Serine/threonine-protein kinase PLK1 inhibitor SureCN3992071 f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00405746 CHEMBL207491 Bioactive AGN-PC-00AVK6

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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