CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10968
Family Name Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16b family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00325361 Functional Category Bioactive
Superfamily Cathepsin K and Cathepsin S Binder Superfamily 13
Class Class 3038

Cousin Family NamesSeedsMembers
HIV-1 protease Inhibitor Atazanavir Family 16 58
Histone deacetylase 1 Inhibitor MS-275 Family 4 41
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
CP-18770 family 6 27
Pol polyprotein inhibitor pyridin-2-ylmethyl N-[(2R)-1-[[(2S,3... 15 8
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16f ... 3 18
Cholecystokinin receptor type A ligand A-65186 family 2 6
Plasmepsin-1 and Plasmepsin-2 inhibitor Statine-like inhibitor... 13 5
Neutrophil elastase inhibitor SureCN7284457 family 4 6
Pol polyprotein inhibitor Carbamic acid, ((2-hydroxy-1,4-bis(p... 21 1
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 8 8
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 5 2
Cruzipain and Cathepsin L1 inhibitor pyridin-3-ylmethyl N-[(2S... 7 4
Metabotropic glutamate receptor 5 ligand AGN-PC-075X3Y family 2 6
Pol polyprotein inhibitor AC1LAHRX family 4 0
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7013744... 2 3
Metabotropic glutamate receptor 5 ligand N-[(5S,7R)-2-(3-chlor... 3 1
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 3
Neuromedin-K receptor ligand AGN-PC-00GCXP family 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00405751 CHEMBL356155 Bioactive N-[(2S)-1-[[(1R)-1-cyano-2-phenylmethoxyethyl]amino]-3-cyclohexyl-1-oxopropan-2-yl]pyridine-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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