CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10970
Family Name Serine/threonine-protein kinase Chk1 inhibitor CHEMBL400574 family
No. of Seeds 26 No. of Other Members 4
Family Centroid CFAMM00405758 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 Binder Superfamily 6
Class Class 2014

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
Serine/threonine-protein kinase Chk1 Inhibitor LY2603618 Family 2 1
Serine/threonine-protein kinase Chk1 inhibitor Chk1_49 family 6 0
Serine/threonine-protein kinase Chk1 and Ribosomal protein S6 ... 4 1
Serine/threonine-protein kinase Chk1 inhibitor N-pyrazinylurea... 1 9
Serine/threonine-protein kinase Chk1 inhibitor AGN-PC-046QRM f... 1 2
Serine/threonine-protein kinase Chk1 inhibitor macrocyclic inh... 24 0
Serine/threonine-protein kinase Chk1 inhibitor CHEMBL398875 fa... 6 0
Serine/threonine-protein kinase Chk1 inhibitor macrocyclic inh... 5 0
Serine/threonine-protein kinase Chk1 inhibitor AGN-PC-076BW0 f... 2 0


External ID

Functional Category

Molecule Name

CFAMM00405755 CHEMBL248952 Bioactive CHEMBL248952
CFAMM00405768 CHEMBL207596 Bioactive N-pyrazinylurea Analog 7
CFAMM00405781 CHEMBL223255 Bioactive macrocyclic inhibitor 18a
CFAMM00405761 CHEMBL381517 Bioactive N-pyrazinylurea Analog 8a
CFAMM00405774 CHEMBL220525 Bioactive macrocyclic inhibitor 17b
CFAMM00405754 CHEMBL248953 Bioactive CHEMBL248953
CFAMM00405767 CHEMBL249764 Bioactive CHEMBL249764
CFAMM00405760 CHEMBL250173 Bioactive CHEMBL250173
CFAMM00405773 CHEMBL387341 Bioactive macrocyclic inhibitor 19a
CFAMM00405766 CHEMBL249765 Bioactive CHEMBL249765
CFAMM00405759 CHEMBL222421 Bioactive macrocyclic inhibitor 17d
CFAMM00405772 CHEMBL248755 Bioactive CHEMBL248755
CFAMM00405765 CHEMBL437772 Bioactive CHEMBL437772
CFAMM00405778 CHEMBL223640 Bioactive macrocyclic inhibitor 19c
CFAMM00405758 CHEMBL400574 Bioactive CHEMBL400574
CFAMM00405771 CHEMBL249363 Bioactive CHEMBL249363
CFAMM00405764 CHEMBL223672 Bioactive macrocyclic inhibitor 17a
CFAMM00405777 CHEMBL400693 Bioactive CHEMBL400693
CFAMM00405757 CHEMBL400575 Bioactive CHEMBL400575
CFAMM00405783 CHEMBL373897 Bioactive macrocyclic inhibitor 5f
CFAMM00405763 CHEMBL223589 Bioactive macrocyclic inhibitor 18c
CFAMM00405776 CHEMBL250375 Bioactive CHEMBL250375
CFAMM00405769 CHEMBL248555 Bioactive CHEMBL248555
CFAMM00405756 CHEMBL400668 Bioactive CHEMBL400668
CFAMM00405782 CHEMBL207606 Bioactive N-pyrazinylurea Analog 8d
CFAMM00405762 CHEMBL220473 Bioactive macrocyclic inhibitor 18b

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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