CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10971
Family Name Sodium-dependent serotonin transporter and Sodium-dependent noradrenaline transporter inhibitor AGN-PC-0761WT family
No. of Seeds 8 No. of Other Members 6
Family Centroid CFAMM00405792 Functional Category Bioactive
Superfamily Sodium-dependent serotonin transporter and Sodium-dependent noradrenaline transporter Binder Superfamily 3
Class Class 832

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Serotonin re-uptake Inhibitor Dexfenfluramine Family 6 31
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 7
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 17 9
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-ri... 5 12
Sodium-dependent serotonin transporter and Sodium-dependent no... 9 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 4
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 7
Sodium-dependent serotonin transporter and Transporter inhibit... 7 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 2
Putative NP ZINC55525127 Family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00405791 CHEMBL207755 Bioactive AGN-PC-0761WM
CFAMM00405789 CHEMBL208178 Bioactive AGN-PC-0761YS
CFAMM00405795 CHEMBL209094 Bioactive 2,3-dihydroxybutanedioic acid;1-[[4-fluoro-2-(trifluoromethyl)phenyl]methyl-piperidin-4-ylamino]-2-methylpropan-2-ol
CFAMM00405788 CHEMBL382248 Bioactive SureCN5995179
CFAMM00405793 CHEMBL377552 Bioactive SureCN5997507
CFAMM00405792 CHEMBL377574 Bioactive AGN-PC-0761WT
CFAMM00405784 CHEMBL208070 Bioactive AGN-PC-0761WV

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27419 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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