CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10972
Family Name Histamine H3 receptor ligand SureCN5218144 family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00405804 Functional Category Bioactive with Natural Product
Superfamily Histamine H3 receptor and Capsid scaffolding protein Binder Superfamily
Class Class 3764

Cousin Family NamesSeedsMembers
Histone deacetylase Inhibitor Abexinostat Family 1 20
Histamine H3 receptor Ligand A-317920 Family 9 240
Histamine H3 receptor Ligand A-349821 Family 49 228
Melatonin receptor type 1A and Melatonin receptor type 1B Liga... 33 98
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Sodium channel protein type 10 subunit alpha and Sodium channe... 2 13
Substance-K receptor ligand 5-chloro-N-[1-[[(2S)-5-[4-(oxan-4-... 2 4
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 4
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 20 9
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 1 14
Lethal(3)malignant brain tumor-like protein 1 and Lysine-speci... 1 6
Prelamin-A/C and Beta-lactamase inhibitor CHEMBL1424193 family 1 0
Mu-type opioid receptor ligand SureCN9379472 family 1 1
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
Prostaglandin E2 receptor EP4 subtype ligand SureCN5653729 family 3 2
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 4 3
Histamine H3 receptor ligand SureCN5221194 family 1 8
Histamine H3 receptor ligand SureCN5216152 family 1 0
Potassium voltage-gated channel subfamily H member 2 and Melan... 5 4
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 4 13
Histamine H1 receptor and Arachidonate 5-lipoxygenase ligand 1... 1 3
Dipeptidyl peptidase 4 inhibitor SureCN5777647 family 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 1
Gonadotropin-releasing hormone receptor ligand N-[[4-[(diamino... 6 4
Capsid scaffolding protein inhibitor AC1LAC52 family 1 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00AWDS ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00405807 CHEMBL208746 Bioactive SureCN5216795
CFAMM00405800 CHEMBL2380804 Bioactive SureCN3326208
CFAMM00405804 CHEMBL208820 Bioactive SureCN5218144
CFAMM00405802 CHEMBL207693 Bioactive 2-[(2S)-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl]-1-benzofuran-5-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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