CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10980
Family Name Serine/threonine-protein kinase Chk1 inhibitor macrocyclic inhibitor 16j family
No. of Seeds 24 No. of Other Members 0
Family Centroid CFAMM00405842 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 Binder Superfamily 6
Class Class 2014

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
Serine/threonine-protein kinase Chk1 Inhibitor LY2603618 Family 2 1
Serine/threonine-protein kinase Chk1 inhibitor Chk1_49 family 6 0
Serine/threonine-protein kinase Chk1 and Ribosomal protein S6 ... 4 1
Serine/threonine-protein kinase Chk1 inhibitor AGN-PC-046QRM f... 1 2
Serine/threonine-protein kinase Chk1 inhibitor CHEMBL400574 fa... 26 4
Serine/threonine-protein kinase Chk1 inhibitor CHEMBL398875 fa... 6 0
Serine/threonine-protein kinase Chk1 inhibitor macrocyclic inh... 5 0
Serine/threonine-protein kinase Chk1 inhibitor AGN-PC-076BW0 f... 2 0


External ID

Functional Category

Molecule Name

CFAMM00405831 CHEMBL399916 Bioactive CHEMBL399916
CFAMM00405844 CHEMBL249364 Bioactive CHEMBL249364
CFAMM00405837 CHEMBL375644 Bioactive macrocyclic inhibitor 15
CFAMM00405843 CHEMBL398757 Bioactive CHEMBL398757
CFAMM00405830 CHEMBL400806 Bioactive CHEMBL400806
CFAMM00405836 CHEMBL248553 Bioactive CHEMBL248553
CFAMM00405829 CHEMBL400805 Bioactive CHEMBL400805
CFAMM00405842 CHEMBL223311 Bioactive macrocyclic inhibitor 16j
CFAMM00405835 CHEMBL376037 Bioactive macrocyclic inhibitor 16f
CFAMM00405828 CHEMBL374334 Bioactive macrocyclic inhibitor 16e
CFAMM00405841 CHEMBL222413 Bioactive macrocyclic inhibitor 16m
CFAMM00405834 CHEMBL219875 Bioactive macrocyclic inhibitor 16g
CFAMM00405827 CHEMBL401196 Bioactive CHEMBL401196
CFAMM00405840 CHEMBL400397 Bioactive CHEMBL400397
CFAMM00405833 CHEMBL373732 Bioactive macrocyclic inhibitor 16b
CFAMM00405846 CHEMBL249155 Bioactive CHEMBL249155
CFAMM00405839 CHEMBL207994 Bioactive 1-(5-Chloro-2,4-Dimethoxyphenyl)-3-(5-Cyanopyrazin-2-Yl)urea
CFAMM00405826 CHEMBL248554 Bioactive CHEMBL248554
CFAMM00405832 CHEMBL219979 Bioactive macrocyclic inhibitor 16o
CFAMM00405845 CHEMBL249156 Bioactive CHEMBL249156
CFAMM00405838 CHEMBL401337 Bioactive CHEMBL401337

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



80838 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543