CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10996
Family Name Coagulation factor X inhibitor 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-sulfamoylphenyl)phenyl]pyrazolo[4,3-d]pyrimidine-3-carboxamide family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00405987 Functional Category Bioactive
Superfamily Coagulation factor X and Prothrombin Binder Superfamily 10
Class Class 3226

Cousin Family NamesSeedsMembers
Coagulation factor X Inhibitor Apixaban Family 34 52
Coagulation factor X and Prothrombin Inhibitor BMS-740808 Family 64 8
Coagulation factor X and Prothrombin inhibitor 2-(3-amino-1,2-... 5 3
Coagulation factor X inhibitor AGN-PC-00FGDC family 11 5
Coagulation factor X and Prothrombin inhibitor 6-[4-[2-[[(3R)-... 15 2
Coagulation factor X and Prothrombin inhibitor 1-(4-methoxyphe... 8 0
Coagulation factor X inhibitor AGN-PC-046QD2 family 6 0
Coagulation factor X inhibitor 2-(4-methoxyphenyl)-N-[5-(2-sul... 1 0
Coagulation factor X inhibitor SureCN5644036 family 30 0
Coagulation factor X inhibitor AGN-PC-077MVW family 5 0


External ID

Functional Category

Molecule Name

CFAMM00405989 CHEMBL213636 Bioactive 6-[2-fluoro-4-(2-sulfamoylphenyl)phenyl]-1-(4-methoxyphenyl)-7-oxopyrazolo[4,3-d]pyrimidine-3-carboxamide
CFAMM00405988 CHEMBL209835 Bioactive methyl 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-sulfamoylphenyl)phenyl]pyrazolo[4,3-d]pyrimidine-3-carboxylate
CFAMM00405987 CHEMBL379986 Bioactive 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-sulfamoylphenyl)phenyl]pyrazolo[4,3-d]pyrimidine-3-carboxamide
CFAMM00405991 CHEMBL437114 Bioactive methyl 6-[2-fluoro-4-(2-sulfamoylphenyl)phenyl]-1-(4-methoxyphenyl)-7-oxopyrazolo[4,3-d]pyrimidine-3-carboxylate
CFAMM00405990 CHEMBL208549 Bioactive 2-[4-[3-cyano-1-(4-methoxyphenyl)-7-oxopyrazolo[4,3-d]pyrimidin-6-yl]phenyl]benzenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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