CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1100
Family Name Beta-1 adrenergic receptor ligand 1-[4-[2-(5-bromo-1H-imidazol-2-yl)ethyl]phenoxy]-3-[2-(3,4-dimethoxyphenyl)ethylamino]propan-2-ol family
No. of Seeds 3 No. of Other Members 8
Family Centroid CFAMM00319455 Functional Category Bioactive with Natural Product
Superfamily Beta-1 adrenergic receptor ligand 1-[4-[2-(5-bromo-1H-imidazol-2-yl)ethyl]phenoxy]-3-[2-(3,4-dimethoxyphenyl)ethylamino]propan-2-ol Superfamily
Class Class 1096

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand 4-(3-phenoxy-propyl)-1h-imidazole... 26 142
5-hydroxytryptamine receptor 3A and Alpha-2A adrenergic recept... 31 24
Aromatase Inhibitor 4-((1h-imidazol-1-yl)methyl)-2h-chromen-2-... 3 69
Cytochrome P450 3A4 Inhibitor SK&F-96365 Family 2 26
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(2-phenoxy-eth... 1 10
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 7 16
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 4 18
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 6 7
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 14 2
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 1 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 3-[2... 2 25
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
D(2) dopamine receptor ligand AGN-PC-07C1V6 family 2 3
Alpha-2A adrenergic receptor and Alpha-1A adrenergic receptor ... 1 3
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 4 6
Alpha-1A adrenergic receptor ligand AGN-PC-0793UT family 3 3
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00319451 CHEMBL11080 Bioactive 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-[4-(1H-imidazol-2-ylmethoxymethyl)phenoxy]propan-2-ol
CFAMM00319455 CHEMBL11112 Bioactive 1-[4-[2-(5-bromo-1H-imidazol-2-yl)ethyl]phenoxy]-3-[2-(3,4-dimethoxyphenyl)ethylamino]propan-2-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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