CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11002
Family Name Suppressor of tumorigenicity 14 protein and Serine protease hepsin inhibitor (2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]pentanediamide family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00240233 Functional Category Bioactive
Superfamily Histone deacetylase 1 and Serine protease hepsin Binder Superfamily
Class Class 4160

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor RWJ-50353 Family 11 95
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-me... 2 45
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 4 3
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-2-(1,3-b... 1 1
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 2 5
Prothrombin inhibitor (2S)-N-[(4-carbamimidoyl-1,3-thiazol-2-y... 3 2
Protease and Capsid scaffolding protein inhibitor AC1LAC7K family 2 5
Coagulation factor X and Prothrombin inhibitor (2S)-2-(benzyls... 4 4
Coagulation factor X and Prothrombin inhibitor AGN-PC-0754DR f... 2 2
Coagulation factor X and Prothrombin inhibitor N-[5-(diaminome... 2 0
Trypsin-1 and Prothrombin inhibitor (6S,8aS)-N-[(2S)-5-(diamin... 1 1
Prothrombin inhibitor (3R,6S,8aS)-N-[5-(diaminomethylideneamin... 2 3
Prothrombin and Cationic trypsin inhibitor 2-ketobenzothiazole... 3 3
Prothrombin inhibitor methyl 2-[(2S)-5-(diaminomethylideneamin... 4 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 3
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-phenyl-1,3-t... 3 4
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
Histone deacetylase 1 inhibitor N',N'-bis[2-(1,3-benzothiazol-... 2 0
Prothrombin and Cationic trypsin inhibitor 2-ketobenzothiazole... 1 0
Cationic trypsin and Prothrombin inhibitor (2S)-N-[1-(1,3-benz... 1 0
Granzyme B inhibitor CHEMBL436855 family 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00406060 CHEMBL2089124 Bioactive (2S)-2-amino-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]propanamide
CFAMM00406059 CHEMBL2089154 Bioactive (2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2R)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]pentanediamide
CFAMM00406058 CHEMBL2089123 Bioactive (2S)-2-amino-N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]pentanediamide
CFAMM00406057 CHEMBL2089122 Bioactive (2S)-N-[(2S)-1-[[(2S)-5-amino-1-(1,3-benzothiazol-2-yl)-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]pentanediamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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