CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11010
Family Name Vascular endothelial growth factor receptor 2 and Fibroblast growth factor receptor 1 ligand 3-[(E)-(5-methoxy-1,3-dihydrobenzimidazol-2-ylidene)-phenylmethyl]-2-oxoindole-5-carboxylic acid family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00283385 Functional Category Bioactive
Superfamily DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Superfamily
Class Class 1528

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Family 3 8
Integrin beta-3 and Integrin alpha-V inhibitor 2-[(2S)-7-[1H-b... 3 6
Thromboxane A2 receptor ligand SureCN9045130 family 4 32
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 39 10
Thyroid hormone receptor beta ligand CHEMBL1325165 family 1 6
Coagulation factor X and Cationic trypsin inhibitor AGN-PC-075... 26 7
Serine/threonine-protein kinase Chk2 inhibitor SureCN3919556 f... 4 8
NS5B protein inhibitor (2E)-1-cyclohexyl-2-(2-fluoro-4-oxocycl... 2 10
Smoothened homolog inhibitor N-[3-(1H-benzimidazol-2-yl)phenyl... 2 1
Platelet-derived growth factor receptor alpha and Vascular end... 3 1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 16 0
5-hydroxytryptamine receptor 2B ligand SureCN1299002 family 2 8
Neuropeptide Y receptor type 5 ligand 1'-(5H-[1,3]dioxolo[4,5-... 2 1
Neuropeptide Y receptor type 5 ligand AGN-PC-02WBQH family 7 1
Neuropeptide Y receptor type 5 ligand AGN-PC-077LX1 family 8 1
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
Tryptase alpha/beta-1 and Tryptase delta inhibitor AGN-PC-0763... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27255 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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