CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11021
Family Name Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-adamantyl)-5-(furan-2-yl)-1-pentylindole-3-carboxamide family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00346132 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 3A and Neuronal acetylcholine receptor subunit alpha-7 Ligand PH-709829 Superfamily
Class Class 918

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Zafirlukast Family 48 78
Melatonin receptor type 1A Ligand Melatonin Family 20 988
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 16
Tyrosine-protein kinase SYK and Low affinity immunoglobulin ep... 1 0
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 11
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 9 12
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 5
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 8 12
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
5-hydroxytryptamine receptor 2B and 5-hydroxytryptamine recept... 1 1
Cathepsin S and Cathepsin K inhibitor N-[(2S)-3-(1-methylcyclo... 2 0
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 11
Histamine H3 receptor ligand SureCN2784306 family 5 3
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
Cannabinoid receptor 1 ligand 5-cyano-N-(3-hydroxy-2,2-dimethy... 17 4
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 11 11
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 7 1
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801290 ... 3 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 2
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 19 10
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Serine/threonine-protein kinase pim-2 and cGMP-dependent prote... 8 1
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Cytosolic phospholipase A2 inhibitor AGN-PC-00BH8R family 6 13
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Mu-type opioid receptor and Mu-type opioid receptor ligand (3S... 6 2
C-C chemokine receptor type 3 and Histamine H1 receptor ligand... 2 2
Seprase and Prolyl endopeptidase inhibitor N-[2-[(2S)-2-cyanop... 1 3
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 4 4
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Substance-P receptor ligand SureCN2139814 family 7 7
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
Endothelin B receptor and Endothelin-1 receptor ligand N-[(2R)... 12 3
Interstitial collagenase and Matrilysin inhibitor (3S,6R,7S)-N... 2 4
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 0
Glycogen synthase kinase-3 beta inhibitor bip-135 family 3 1
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 6 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 0
Protein kinase C theta type and Protein kinase C delta type in... 13 0
Bombesin receptor subtype-3 ligand 2-[[(E)-furan-2-ylmethylide... 2 4
Sodium-dependent serotonin transporter inhibitor SureCN5477150... 4 1
Mitogen-activated protein kinase 14 inhibitor SureCN4508019 fa... 1 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00406178 CHEMBL2087106 Bioactive N-(1-adamantyl)-5-(furan-2-yl)-1-prop-2-enylindole-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23964 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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