CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11022
Family Name Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-adamantyl)-1-pentyl-5-thiophen-2-ylindole-3-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00406182 Functional Category Bioactive
Superfamily Cannabinoid receptor 2 and Cannabinoid receptor 1 Binder Superfamily 8
Class Class 1827

Cousin Family NamesSeedsMembers
D(1A) dopamine receptor ligand ergot alkaloid Methylergonovine... 22 170
Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
D(3) dopamine receptor Ligand SB-277011 Family 13 178
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
XL-888 family 16 85
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(thiophen... 9 66
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 37 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-2... 8 1
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Poly [ADP-ribose] polymerase 1 Inhibitor 3-ethenylquinoline-8-... 8 4
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 4 10
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Glutamate receptor 1 Ligand Piriqualone Family 8 67
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 27
Endothelin B receptor Ligand IRL-2500 Family 34 87
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745NK family 2 6
Substance-P receptor ligand N-[(1S,2R)-2-[[(1R)-1-[methyl-(2-p... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Sodium-dependent serotonin transporter and Sodium-dependent do... 10 2
Serine/threonine-protein kinase pim-3 and Serine/threonine-pro... 4 6
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
Serine/threonine-protein kinase D3 and Protein kinase C delta ... 3 10
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 2
Serine/threonine-protein kinase D3 and Protein kinase C delta ... 3 0
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QJ7P family 2 0
ALK tyrosine kinase receptor and Insulin receptor ligand 9-eth... 9 8
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 18 3
Protein kinase C beta type and Protein kinase C delta type inh... 1 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 16
Coagulation factor X inhibitor AGN-PC-030DHH family 1 0
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
Histone deacetylase 1 inhibitor 5-[5-[[(2-chlorophenyl)methyla... 4 1
Glutamate receptor ionotropic, NMDA 2B ligand N-[3-[2-(4-benzy... 2 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
Platelet-activating factor receptor ligand (1-ethylindol-3-yl)... 17 13
Platelet-activating factor receptor ligand N,N-diethyl-3-[(4R)... 11 0
Platelet-activating factor receptor ligand (6-bromo-1H-indol-3... 2 0
Sodium-dependent serotonin transporter and D(2) dopamine recep... 1 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0
Protein kinase C theta type and Tyrosine-protein kinase Fyn in... 4 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 2 0
1-(thiophen-2-yl)-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00406182 CHEMBL2087109 Bioactive N-(1-adamantyl)-1-pentyl-5-thiophen-2-ylindole-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44484 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543