CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11035
Family Name Activated CDC42 kinase 1 inhibitor 6-[4-(2-morpholin-4-ylethoxy)phenyl]-N-[[(2S)-oxolan-2-yl]methyl]-5-phenylfuro[2,3-d]pyrimidin-4-amine family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00223890 Functional Category Bioactive
Superfamily Prelamin-A/C and Activated CDC42 kinase 1 Binder Superfamily
Class Class 1877

Cousin Family NamesSeedsMembers
MK-6096 family 3 69
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 37
Peptide deformylase, mitochondrial Inhibitor Furo[2,3d]pyrimid... 2 10
Serine/threonine-protein kinase Chk1 Inhibitor N-(5,6-diphenyl... 9 100
5-hydroxytryptamine receptor 2C Ligand 6-methyl-4-(piperazin-1... 1 0
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 2 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 6 1
Vascular endothelial growth factor receptor 1 and Receptor-typ... 2 11
Vascular endothelial growth factor receptor 1 ligand CHEMBL197... 1 2
Activated CDC42 kinase 1 inhibitor 6-(4-methylsulfonylphenyl)-... 2 0
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 2 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Adenosine kinase inhibitor AGN-PC-0757MS family 2 0
Neuropeptide Y receptor type 5 ligand SureCN2658856 family 6 0
Tyrosine-protein kinase JAK3 and Activated CDC42 kinase 1 inhi... 4 1
Nonstructural protein 1 and Beta-lactamase inhibitor CHEMBL138... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00406321 CHEMBL2087876 Bioactive 6-[4-[2-(dimethylamino)ethoxy]phenyl]-5-phenyl-N-(thiolan-2-ylmethyl)furo[2,3-d]pyrimidin-4-amine
CFAMM00406320 CHEMBL2087874 Bioactive 6-[4-[2-(dimethylamino)ethoxy]phenyl]-N-(1,3-dithiolan-2-ylmethyl)-5-phenylfuro[2,3-d]pyrimidin-4-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26410 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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