CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11045
Family Name Fibroblast growth factor receptor 1 and Vascular endothelial growth factor receptor 2 ligand 5-bromo-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-[5-(2-phenylethyl)-1H-pyrazol-3-yl]pyrimidine-2,4-diamine family
No. of Seeds 3 No. of Other Members 16
Family Centroid CFAMM00406398 Functional Category Bioactive
Superfamily Aurora kinase A and GABA theta subunit Binder Superfamily
Class Class 1228

Cousin Family NamesSeedsMembers
Progesterone receptor Ligand GSK-1564023A Family 1 11
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Fibroblast growth factor receptor 1 and Vascular endothelial g... 3 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 1 0
Tyrosine-protein kinase JAK2 and Cytochrome P450 1A2 inhibitor... 1 0
Mitogen-activated protein kinase 14 inhibitor isoxazole 80 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00406390 CHEMBL2088100 Bioactive 2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-[5-(2-phenylethyl)-1H-pyrazol-3-yl]pyrimidine-2,4-diamine
CFAMM00406399 CHEMBL2088094 Bioactive 5-bromo-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-(5-propyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
CFAMM00406398 CHEMBL2088095 Bioactive 5-bromo-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-[5-(2-phenylethyl)-1H-pyrazol-3-yl]pyrimidine-2,4-diamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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