CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11047
Family Name C-C chemokine receptor type 2 ligand N-[(1S,2R,4R)-2-(benzenesulfonylmethyl)-4-[methyl(propan-2-yl)amino]cyclohexyl]-2-[4-(trifluoromethyl)-1H-benzimidazol-2-yl]acetamide family
No. of Seeds 7 No. of Other Members 9
Family Centroid CFAMM00406415 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 and Cytochrome P450 1A2 Binder Superfamily
Class Class 2756

Cousin Family NamesSeedsMembers
Cannabinoid receptor 2 ligand 2-tert-butyl-5-ethylsulfonyl-1-(... 28 32
Neuropeptide Y receptor type 5 ligand 1-phenyl-5-[6-(2,2,2-tri... 4 1
Neuropeptide Y receptor type 5 ligand 2-(3-phenylpiperidin-1-y... 6 2


External ID

Functional Category

Molecule Name

CFAMM00406415 CHEMBL2088211 Bioactive N-[(1S,2R,4R)-2-(benzenesulfonylmethyl)-4-[methyl(propan-2-yl)amino]cyclohexyl]-2-[4-(trifluoromethyl)-1H-benzimidazol-2-yl]acetamide
CFAMM00406414 CHEMBL2088388 Bioactive 1-[(1S,2R,4R)-2-(benzenesulfonylmethyl)-4-[methyl(propan-2-yl)amino]cyclohexyl]-3-[4-(trifluoromethyl)-1H-benzimidazol-2-yl]pyrrolidin-2-one
CFAMM00406413 CHEMBL2088389 Bioactive 1-[(1S,2R,4R)-2-(benzenesulfonylmethyl)-4-[ethyl(propan-2-yl)amino]cyclohexyl]-3-[4-(trifluoromethyl)-1H-benzimidazol-2-yl]pyrrolidin-2-one
CFAMM00406411 CHEMBL2088379 Bioactive N-[(1S,2R,4R)-2-[(4-ethylphenyl)sulfonylmethyl]-4-[methyl(propan-2-yl)amino]cyclohexyl]-2-[4-(trifluoromethyl)-1H-benzimidazol-2-yl]acetamide
CFAMM00406417 CHEMBL2088212 Bioactive N-[(1S,2R,4R)-2-[(4-bromophenyl)sulfonylmethyl]-4-[methyl(propan-2-yl)amino]cyclohexyl]-2-[4-(trifluoromethyl)-1H-benzimidazol-2-yl]acetamide
CFAMM00406410 CHEMBL2088380 Bioactive N-[(1S,2R,4R)-2-[(4-cyanophenyl)sulfonylmethyl]-4-[methyl(propan-2-yl)amino]cyclohexyl]-2-[4-(trifluoromethyl)-1H-benzimidazol-2-yl]acetamide
CFAMM00406409 CHEMBL2088378 Bioactive N-[(1S,2R,4R)-2-[(4-methylphenyl)sulfonylmethyl]-4-[methyl(propan-2-yl)amino]cyclohexyl]-2-[4-(trifluoromethyl)-1H-benzimidazol-2-yl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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