CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1105
Family Name Neutrophil elastase inhibitor benzyl N-[2-(4-aminophenyl)-6-oxo-1-[2-oxo-2-[(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)amino]ethyl]pyrimidin-5-yl]carbamate family
No. of Seeds 4 No. of Other Members 23
Family Centroid CFAMM00319496 Functional Category Bioactive
Superfamily Integrin beta-3 and Integrin alpha-V Binder Superfamily 6
Class Class 1500

Cousin Family NamesSeedsMembers
Flovagatran family 12 546
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Neutrophil elastase inhibitor AGN-PC-0745AS family 2 9
Neutrophil elastase inhibitor SureCN7276766 family 3 6
Neutrophil elastase inhibitor SureCN7276506 family 2 7
Neutrophil elastase inhibitor SureCN7284457 family 4 6
Neutrophil elastase and Chymotrypsin-C inhibitor benzyl N-[6-(... 3 6
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 8 8
Neutrophil elastase inhibitor benzyl 2-[2,4,8-trioxo-7-[2-oxo-... 2 2
Neutrophil elastase inhibitor benzyl N-[(2S)-1-[(2S)-2-[[(3S)-... 4 0
Chymase and Chymotrypsin-C inhibitor 4-[[2-[5-amino-2-(3-methy... 4 14
Neutrophil elastase inhibitor SureCN7471252 family 2 0
Neutrophil elastase inhibitor SureCN7273831 family 2 2
Protease inhibitor AC1O54RX family 2 4
Neutrophil elastase inhibitor AGN-PC-0745BY family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00319506 CHEMBL11403 Bioactive SureCN9583963
CFAMM00319519 CHEMBL11098 Bioactive SureCN9583983
CFAMM00319518 CHEMBL11347 Bioactive benzyl N-[2-(4-formamidophenyl)-6-oxo-1-[2-oxo-2-[(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)amino]ethyl]pyrimidin-5-yl]carbamate
CFAMM00319496 CHEMBL11398 Bioactive benzyl N-[2-(4-aminophenyl)-6-oxo-1-[2-oxo-2-[(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)amino]ethyl]pyrimidin-5-yl]carbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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