CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11071
Family Name Adenosine receptor A3 ligand (1R,2R,3S,4R,5S)-4-[2-[2-(2-chlorophenyl)ethynyl]-6-(methylamino)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00406620 Functional Category Bioactive
Superfamily Adenosine receptor A3 and Adenosine receptor A2a Binder Superfamily
Class Class 1014

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Adenosine receptor A3 Ligand CF101 Family 24 560
Adenosine receptor A2a Ligand MRE-0094 Family 10 108
Equilibrative nucleoside/nucleobase transporter Inhibitor Nitr... 23 98
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 7 72
Adenosine receptor A1 and Adenosine receptor A2a Ligand GW-328... 26 94
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 21 57
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-[(4-... 15 9
Adenosine receptor A2a and Adenosine receptor A3 Ligand 2-(3''... 8 10
Inositol 1,4,5-trisphosphate receptor type 3 Ligand 5'-deoxy-5... 11 8
Adenosine receptor A3 ligand (1S,2R,3S,4R,5S)-2,3-dihydroxy-N-... 30 54
Adenosine receptor A3 and Adenosine receptor A2a ligand (1R,2R... 12 17
Adenosine receptor A3 and Adenosine receptor A1 ligand (1S,2R,... 32 9
Adenosine receptor A3 ligand 3-[2-[6-[(3-chlorophenyl)methylam... 1 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (1S,2R,... 6 0
Adenosine receptor A3 ligand (2R,3R,4S)-2-[2-chloro-6-[(3-fluo... 6 7
Adenosine receptor A1 ligand 3-chloro-N-[(2S,3R,4R,5R)-5-[6-(c... 1 0
Adenosine receptor A3 and Adenosine receptor A2a ligand (1S,2R... 3 0
DNA polymerase III PolC-type and DNA polymerase III subunit al... 11 10
78 kDa glucose-regulated protein and Heat shock cognate 71 kDa... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00406620 CHEMBL2089336 Bioactive (1R,2R,3S,4R,5S)-4-[2-[2-(2-chlorophenyl)ethynyl]-6-(methylamino)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
CFAMM00406619 CHEMBL2089340 Bioactive (1R,2R,3S,4R,5S)-4-[2-[2-(2-chlorophenyl)ethynyl]-6-(ethylamino)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
CFAMM00406617 CHEMBL523797 Bioactive (1R,2R,3S,4R,5S)-4-[2-chloro-6-[(3-chlorophenyl)methylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
CFAMM00406621 CHEMBL2089338 Bioactive (1R,2R,3S,4R,5S)-4-[2-[2-(2-chlorophenyl)ethynyl]-6-(methoxyamino)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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