CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11087
Family Name Substance-P receptor and Potassium voltage-gated channel subfamily H member 2 ligand (3R,5S,6S)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-6-(4-fluorophenyl)-3-methylazepan-2-one family
No. of Seeds 10 No. of Other Members 0
Family Centroid CFAMM00406698 Functional Category Bioactive
Superfamily Substance-P receptor and Lethal factor Binder Superfamily
Class Class 3563

Cousin Family NamesSeedsMembers
Substance-P receptor Ligand L-733060 Family 19 71
Substance-P receptor Ligand SCH-388714 Family 26 8
Substance-P receptor ligand (1S,2R,5aS,7S,8aR,8bS)-7-amino-2-[... 12 2
Substance-P receptor ligand 1-[4-[[3,5-bis(trifluoromethyl)phe... 5 8
Substance-P receptor ligand 1-amino-3-[[(1R)-1-[3,5-bis(triflu... 5 0
Substance-P receptor ligand 1-[(1R,2S,3S)-3-[[3,5-bis(trifluor... 7 2
Substance-P receptor ligand 2-[[(1R,2S,3S)-3-[(1R)-1-[3,5-bis(... 5 0
Substance-P receptor ligand 1-[3-[[(1R)-1-[3,5-bis(trifluorome... 2 0
Substance-P receptor ligand 2-[[(1R,2S,3S)-3-[[3,5-bis(trifluo... 6 0
Substance-P receptor ligand (5R)-5-[[[(1R,2S,3S)-3-[(1R)-1-[3,... 6 0
Substance-P receptor ligand (1R,2S,3S)-3-[(1R)-1-[3,5-bis(trif... 8 0
Substance-P receptor ligand 1-[(3S,4R)-3-[(1R)-1-[3,5-bis(trif... 9 0
Substance-P receptor ligand (5S)-5-[(3S,4R)-3-[(1R)-1-[3,5-bis... 3 0
Putative NP ZINC04026324 Family 6 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00406705 CHEMBL380680 Bioactive (5S,6S)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-6-(4-fluorophenyl)azepan-2-one
CFAMM00406698 CHEMBL209456 Bioactive (3R,5S,6S)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-6-(4-fluorophenyl)-3-methylazepan-2-one
CFAMM00406704 CHEMBL413279 Bioactive (4R,5S,7R)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-1,7-dimethylazepan-2-one
CFAMM00406697 CHEMBL378663 Bioactive (3R,5S,6S)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-6-(4-fluorophenyl)-1,3-dimethylazepan-2-one
CFAMM00406703 CHEMBL209240 Bioactive (5S,6S,7S)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-6-(4-fluorophenyl)-1,7-dimethylazepan-2-one
CFAMM00406702 CHEMBL382255 Bioactive (4R,5S)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-1-methylazepan-2-one
CFAMM00406701 CHEMBL425956 Bioactive (5S,6S,7S)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-6-(4-fluorophenyl)-7-methylazepan-2-one
CFAMM00406700 CHEMBL379816 Bioactive (4R,5S)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)azepan-2-one
CFAMM00406706 CHEMBL209407 Bioactive (4R,5S,7R)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-7-methylazepan-2-one
CFAMM00406699 CHEMBL437878 Bioactive (5S,6S)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-6-(4-fluorophenyl)-1-methylazepan-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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