CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11116
Family Name Transporter and Sodium-dependent serotonin transporter inhibitor (3S,6S)-6-benzhydryl-N-(1H-indol-5-ylmethyl)oxan-3-amine family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00379695 Functional Category Bioactive
Superfamily Grt 6005/06 Superfamily
Class Class 1304

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 4 171
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Grt 6005/06 family 4 22
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
D(2) dopamine receptor Ligand SLV-314 Family 19 69
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 18 17
Protein kinase C theta type and Protein kinase C delta type in... 16 8
Neuronal acetylcholine receptor subunit alpha-7 and Acetylchol... 6 9
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 7 14
Glucocorticoid receptor ligand SureCN5650626 family 17 25
Glucocorticoid receptor and Progesterone receptor ligand [(3R,... 6 2
Glucocorticoid receptor ligand SureCN4198717 family 5 0
Glucocorticoid receptor and Androgen receptor ligand AGN-PC-0A... 3 0
Glucocorticoid receptor ligand AGN-PC-0A9RHA family 1 2
CGMP-dependent protein kinase inhibitor AGN-PC-075XII family 25 7
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[2-(1H-ind... 1 0
CGMP-dependent protein kinase inhibitor AGN-PC-075XJ0 family 9 1
5-hydroxytryptamine receptor 2A ligand (3R,4R)-3-(2-phenyl-1H-... 1 18
CGMP-dependent protein kinase inhibitor methyl 2-[[4-[5-(4-flu... 6 1
D(1A) dopamine receptor and D(3) dopamine receptor ligand RU-2... 3 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
CGMP-dependent protein kinase inhibitor AGN-PC-0761UG family 1 2
CGMP-dependent protein kinase inhibitor AGN-PC-078XQ0 family 1 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 7
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 1


External ID

Functional Category

Molecule Name

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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