CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11128
Family Name Dihydrofolate reductase and Bifunctional dihydrofolate reductase-thymidylate synthase inhibitor AC1LA65J family
No. of Seeds 4 No. of Other Members 9
Family Centroid CFAMM00407011 Functional Category Bioactive
Superfamily Dihydrofolate reductase and Sodium channel protein type 2 subunit alpha Binder Superfamily
Class Class 3999

Cousin Family NamesSeedsMembers
NMDA receptor Ligand CNS-5161 Family 3 18
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 14 78
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 5 3
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00407011 CHEMBL20975 Bioactive AC1LA65J
CFAMM00407017 CHEMBL21031 Bioactive NSC368891
CFAMM00407015 CHEMBL31004 Bioactive 6,6-dimethyl-1-[4-(phenylsulfanylmethyl)phenyl]-1,3,5-triazine-2,4-diamine
CFAMM00407014 CHEMBL21077 Bioactive AGN-PC-00SITO

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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