CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11144
Family Name Coagulation factor X and Prothrombin inhibitor 1-(4-methoxyphenyl)-7-oxo-6-[4-[2-(pyrrolidin-1-ylmethyl)phenyl]phenyl]pyrazolo[4,3-d]pyrimidine-3-carboxamide family
No. of Seeds 8 No. of Other Members 0
Family Centroid CFAMM00407132 Functional Category Bioactive
Superfamily Coagulation factor X and Prothrombin Binder Superfamily 10
Class Class 3226

Cousin Family NamesSeedsMembers
Coagulation factor X Inhibitor Apixaban Family 34 52
Coagulation factor IX and Coagulation factor X Inhibitor Razax... 22 34
Coagulation factor X and Prothrombin Inhibitor BMS-740808 Family 64 8
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
Coagulation factor X and Prothrombin inhibitor 2-(3-amino-1,2-... 5 3
Coagulation factor X inhibitor AGN-PC-00FGDC family 11 5
Coagulation factor X inhibitor AGN-PC-046RMH family 5 0
Coagulation factor X and Prothrombin inhibitor 6-[4-[2-[[(3R)-... 15 2
Coagulation factor X inhibitor 1-(4-methoxyphenyl)-7-oxo-6-[4-... 5 0
Coagulation factor X inhibitor AGN-PC-03K47Q family 3 0
Coagulation factor X inhibitor AGN-PC-046QD2 family 6 0
Coagulation factor X and Prothrombin inhibitor 1-(3-amino-1,2-... 9 0
Coagulation factor X inhibitor SureCN6785555 family 7 0
Coagulation factor X and Prothrombin inhibitor 6-[4-[2-[[(3R)-... 1 0
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Adenosine receptor A3 and Adenosine receptor A1 ligand N-[2-(4... 3 2
Coagulation factor X and Prothrombin inhibitor 6-[4-[2-[[(3R)-... 7 0
Coagulation factor X inhibitor AGN-PC-046RMQ family 1 0
Vascular endothelial growth factor receptor 2 and Vascular end... 2 3
Coagulation factor X inhibitor SureCN5641901 family 5 0
Coagulation factor X inhibitor AGN-PC-077MYE family 16 0
Coagulation factor X inhibitor SureCN5644036 family 30 0
Coagulation factor X inhibitor AGN-PC-077MVW family 5 0
Coagulation factor X inhibitor SureCN5644554 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00407135 CHEMBL379937 Bioactive AGN-PC-02YW2W
CFAMM00407134 CHEMBL210120 Bioactive AGN-PC-046QCN
CFAMM00407133 CHEMBL210121 Bioactive AGN-PC-046QCO
CFAMM00407132 CHEMBL384526 Bioactive 1-(4-methoxyphenyl)-7-oxo-6-[4-[2-(pyrrolidin-1-ylmethyl)phenyl]phenyl]pyrazolo[4,3-d]pyrimidine-3-carboxamide
CFAMM00407131 CHEMBL211386 Bioactive 6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-1-(4-methoxyphenyl)-7-oxopyrazolo[4,3-d]pyrimidine-3-carboxamide
CFAMM00407130 CHEMBL385140 Bioactive 1-(4-methoxyphenyl)-7-oxo-6-[4-[2-(pyrrolidin-1-ylmethyl)phenyl]phenyl]pyrazolo[4,3-d]pyrimidine-3-carbonitrile
CFAMM00407136 CHEMBL378294 Bioactive AGN-PC-02YW2S

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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