CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11153
Family Name D(4) dopamine receptor and D(3) dopamine receptor ligand AGN-PC-00BWXO family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00251403 Functional Category Bioactive
Superfamily Macrophage metalloelastase Inhibitor Ageladine A Superfamily
Class Class 202

Cousin Family NamesSeedsMembers
Benzodiazepine receptor Ligand Midazolam Family 5 160
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
HCV NS4B protein Inhibitor Clemizole Family 2 43
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 13 55
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Histamine H3 receptor Ligand SCH79687 Family 11 29
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 5 7
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Adenosine receptor A1 Ligand Phenyl-(9-phenyl-9h-purin-6-yl)-a... 7 12
Adenosine receptor A3 and Dual specificity mitogen-activated p... 5 27
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Proto-oncogene tyrosine-protein kinase Src Inhibitor CGP-62464... 3 10
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 9
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 7 7
Platelet-activating factor receptor ligand SureCN9523843 family 4 4
Platelet-activating factor receptor ligand SureCN9383514 family 4 1
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 0
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 2 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 5 0
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 7
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Vasopressin V1a receptor and Vasopressin V2 receptor ligand 8-... 6 2
Ribosomal protein S6 kinase alpha-5 inhibitor AGN-PC-075HAD fa... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 0
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
D(4) dopamine receptor and Alpha-1D adrenergic receptor ligand... 3 3
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[1-... 5 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 4
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 2 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 3
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 5 2
Cathepsin K inhibitor SureCN4141224 family 3 0
Mitogen-activated protein kinase 10 inhibitor CYCLOPROPYL-{4-[... 2 1
Nociceptin receptor and Potassium voltage-gated channel subfam... 5 2
Adenosine receptor A1 and Adenosine receptor A2b ligand SureCN... 2 3
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-a]pyridine der... 4 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
Cyclin-dependent kinase 2 inhibitor SureCN3549598 family 3 1
5-hydroxytryptamine receptor 3A ligand AGN-PC-077D8K family 3 1
Lysosomal Pro-X carboxypeptidase inhibitor 1-[6-[(2S)-2-(5,6-d... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543