CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11160
Family Name Cyclin-dependent kinase 6 and Cyclin-dependent kinase 4 inhibitor AGN-PC-00RWX5 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00126964 Functional Category Bioactive
Superfamily Aurora kinase B and Aurora kinase A Inhibitor CYC116 Superfamily
Class Class 817

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 4 23
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 11 20
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-ethy... 2 2
Histamine H3 receptor Ligand 2-(1,4'-bipiperidin-1'-yl)thiazol... 2 23
Tyrosine-protein kinase JAK2 and Potassium voltage-gated chann... 1 0
Mitogen-activated protein kinase 14 and LIM domain kinase 1 in... 4 19
Serine/threonine-protein kinase Chk1 inhibitor 5-[5-(1-methylp... 3 2
Ketohexokinase inhibitor 4-N-(2-methylsulfanylphenyl)-2-pipera... 6 23
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor CDK Inhibito... 8 3
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 2 6
Aurora kinase B and Tyrosine-protein kinase ITK/TSK inhibitor ... 2 2
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 5 0
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 2 2
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27745 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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