CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1117
Family Name Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-1-benzoyl-3-[3-(diaminomethylideneamino)propyl]-4-oxoazetidine-2-carboxylic acid family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00319650 Functional Category Bioactive with Natural Product
Superfamily Tryptase delta and Tryptase alpha/beta-1 Binder Superfamily 2
Class Class 2034

Cousin Family NamesSeedsMembers
Iofolastat I-124 family 6 33
Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
Integrin beta-3 Inhibitor Sibrafiban Family 4 6
Integrin beta-3 Inhibitor L-709780 Family 9 10
Integrin beta-3 Inhibitor DMP-728 Family 3 0
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-3-[... 13 17
Integrin beta-3 and Integrin alpha-V inhibitor 2-[(1R,5S,11S,1... 8 2
Integrin alpha-V and Integrin beta-5 inhibitor 2-[(2S,5R,8S,11... 2 1
Glutamate carboxypeptidase 2 inhibitor (2S)-2-[[(1R)-1-carboxy... 8 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R,6S,12S)-6... 7 0
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-1-[... 8 0
Tryptase alpha/beta-1 and Tryptase delta inhibitor SureCN33323... 1 3
Angiotensin-converting enzyme inhibitor SureCN7263641 family 2 11
Genome polyprotein inhibitor Benzoyl-KKR-H family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00319651 CHEMBL111548 Bioactive (2S,3R)-1-(4-benzoylpiperazine-1-carbonyl)-3-[3-(diaminomethylideneamino)propyl]-4-oxoazetidine-2-carboxylic acid
CFAMM00319650 CHEMBL111270 Bioactive (2S,3R)-1-benzoyl-3-[3-(diaminomethylideneamino)propyl]-4-oxoazetidine-2-carboxylic acid
CFAMM00319648 CHEMBL111250 Bioactive (2S,3R)-3-[3-(diaminomethylideneamino)propyl]-4-oxo-1-(4-phenylbenzoyl)azetidine-2-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45860 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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