CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1118
Family Name Peroxisome proliferator-activated receptor alpha and Peroxisome proliferator-activated receptor gamma ligand SureCN7077858 family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00299752 Functional Category Bioactive
Superfamily Prothrombin and Neutrophil elastase Binder Superfamily
Class Class 605

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Arachidonate 5-lipoxygenase Inhibitor Lonapalene Family 1 31
Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Oxi4503 family 4 27
Free fatty acid receptor 1 Ligand TAK-875 Family 2 54
Integrase Inhibitor L-708,906 Family 1 8
Endothelin-1 receptor Ligand PD156707 Family 41 211
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Tubulin beta chain Inhibitor Combretastatin Family 3 5
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
NAD(P)H dehydrogenase [quinone] 1 Inhibitor Ethyl Bis(4-hydrox... 5 7
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Heat shock cognate 71 kDa protein Inhibitor NSC-119913 Family 2 1
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 0
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 6 6
Peroxisome proliferator-activated receptor alpha and Peroxisom... 4 28
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 4
Peroxisome proliferator-activated receptor alpha and Peroxisom... 7 6
Endothelin-1 receptor ligand (2S)-2-(1,3-benzodioxol-5-yl)-4-m... 17 0
Peroxisome proliferator-activated receptor alpha ligand SureCN... 9 3
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 0
Peroxisome proliferator-activated receptor alpha ligand AGN-PC... 5 2
Endothelin-1 receptor ligand SureCN8117947 family 1 3
Peroxisome proliferator-activated receptor delta and Peroxisom... 4 2
Endothelin-1 receptor and Endothelin B receptor ligand SureCN7... 2 2
Free fatty acid receptor 1 ligand 2-[(8S)-3-(3-bromophenyl)-2,... 2 3
Free fatty acid receptor 1 ligand 2-[(3R,8S)-3-(3-chlorophenyl... 2 2
Free fatty acid receptor 1 ligand 2-[(8S)-3-[5-[2-chloro-4-(3-... 3 3
Cytosolic phospholipase A2 beta inhibitor 2-[3-[3-(4-decoxyphe... 1 0
Multidrug resistance protein 1 inhibitor CHEMBL1 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00319658 CHEMBL214921 Bioactive SureCN5990681

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543