CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11189
Family Name Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carboxyphenyl)methyl]-5-tritioimidazol-4-yl]methylamino]benzoic acid family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00407420 Functional Category Bioactive with Natural Product
Superfamily Type-1A angiotensin II receptor and Collagenase 3 Binder Superfamily
Class Class 307

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Olmesartan Family 13 65
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor TAK-700 Family 1 6
Eluxadoline family 4 85
Farnesyltransferase beta subunit, putative and Protein farnesy... 20 81
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Family 3 8
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Acetylcholinesterase inhibitor SureCN251059 family 2 16
Bombesin receptor subtype-3 ligand AGN-PC-07ZAKV family 13 23
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 11 22
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 2
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 7 11
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 7 3
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 5 0
Adenosine receptor A1 ligand AGN-PC-07PMLW family 6 4
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[[4-[(2-c... 3 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 25
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 3
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 1
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 3... 5 14
Endothelin-1 receptor and Endothelin B receptor ligand SureCN9... 3 10
Delta-type opioid receptor ligand ethyl N-[3-[(R)-[4-[ethyl(me... 2 6
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 3-methyl-4... 15 14
Lysine--tRNA ligase inhibitor 4-[[2-(2-piperazin-1-ylpyridin-4... 2 0
Aurora kinase A inhibitor Bisanilinopyrimidine, 6i family 1 0
Aurora kinase A inhibitor Bisanilinopyrimidine, 6j family 2 1
Type-1 angiotensin II receptor ligand 2-butyl-3-[[4-(2-carboxy... 1 7
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor (2S)-2... 2 4
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Thromboxane-A synthase inhibitor AGN-PC-00NE8C family 2 3
Neuropeptide Y receptor type 5 ligand AGN-PC-077LX1 family 8 1
Thromboxane-A synthase inhibitor SureCN11474904 family 1 6
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 20
Type-1 angiotensin II receptor ligand AGN-PC-025PHO family 3 21
Ribosomal protein S6 kinase beta-1 inhibitor AGN-PC-07ZBLV family 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00407421 CHEMBL309309 Bioactive SureCN9213511
CFAMM00407420 CHEMBL2111971 Bioactive 2-[[2-butyl-3-[(4-carboxyphenyl)methyl]-5-tritioimidazol-4-yl]methylamino]benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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