CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11206
Family Name 5-hydroxytryptamine receptor 1A ligand (3S)-3-[4-(7,9-dioxo-8-azaspiro[4.5]decan-8-yl)butyl-(2-methylpropyl)amino]-N-methyl-3,4-dihydro-2H-chromene-5-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00407524 Functional Category Bioactive
Superfamily Sodium channel protein type 5 subunit alpha Ligand Flecainide Superfamily
Class Class 302

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 23
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 10 6
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 2
Renin inhibitor N-[(2S,4S,5S,7S)-7-[2-(1-acetylpiperidin-4-yl)... 2 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 1
Growth hormone secretagogue receptor type 1 ligand 2-(2-acetyl... 2 0
Growth hormone secretagogue receptor type 1 ligand 2-[(2S)-1-[... 2 0
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 1 3
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 15 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
Renin inhibitor N-[(2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy... 5 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
5-hydroxytryptamine receptor 1A ligand AGN-PC-074R8E family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00407524 CHEMBL2112379 Bioactive (3S)-3-[4-(7,9-dioxo-8-azaspiro[4.5]decan-8-yl)butyl-(2-methylpropyl)amino]-N-methyl-3,4-dihydro-2H-chromene-5-carboxamide
CFAMM00407523 CHEMBL95215 Bioactive 3-[4-(7,9-dioxo-8-azaspiro[4.5]decan-8-yl)butyl-propylamino]-N-methyl-3,4-dihydro-2H-chromene-5-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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