CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11215
Family Name Disintegrin and metalloproteinase domain-containing protein 17 and 72 kDa type IV collagenase inhibitor 3-[(4-but-2-ynoxyphenyl)sulfonylmethyl]-N-hydroxy-1-(2-methylpropanoyl)piperidine-3-carboxamide family
No. of Seeds 12 No. of Other Members 1
Family Centroid CFAMM00255095 Functional Category Bioactive
Superfamily Disintegrin and metalloproteinase domain-containing protein 17 and 72 kDa type IV collagenase Binder Superfamily
Class Class 2056

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 15 129
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 3 28
Disintegrin and metalloproteinase domain-containing protein 17... 25 33
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
72 kDa type IV collagenase and Collagenase 3 inhibitor N-hydro... 3 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Lethal(3)malignant brain tumor-like protein 1 inhibitor CHEMBL... 1 5
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Collagenase 3 and 72 kDa type IV collagenase inhibitor 4-[4-[4... 4 4
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 3 5
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 3 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 19 11
72 kDa type IV collagenase and Collagenase 3 inhibitor 1-ethyl... 11 5
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 3 15
Disintegrin and metalloproteinase domain-containing protein 17... 5 2
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 4 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
Collagenase 3 and Neutrophil collagenase inhibitor (3R)-1-hydr... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 7 1
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 3 0
Interstitial collagenase inhibitor AGN-PC-075XO4 family 1 0
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 5
Disintegrin and metalloproteinase domain-containing protein 17... 6 0
Disintegrin and metalloproteinase domain-containing protein 17... 3 16
Disintegrin and metalloproteinase domain-containing protein 17... 9 3
Disintegrin and metalloproteinase domain-containing protein 17... 3 3
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-[(4-b... 3 1
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 1-hydro... 1 1
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 13 3
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 4 4
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 6 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor AGN-PC-... 2 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor N-hydro... 3 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-[4-[(... 5 1
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor 3-cyclo... 5 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 4
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 2
Interstitial collagenase and Matrix metalloproteinase-9 inhibi... 1 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 1 0
Collagenase 3 and Interstitial collagenase inhibitor 2-(4-brom... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00407572 CHEMBL250094 Bioactive ethyl 3-[(4-but-2-ynoxyphenyl)sulfonylmethyl]-3-(hydroxycarbamoyl)piperidine-1-carboxylate
CFAMM00407571 CHEMBL399929 Bioactive 3-[(4-but-2-ynoxyphenyl)sulfonylmethyl]-1-N,1-N-diethyl-3-N-hydroxypiperidine-1,3-dicarboxamide
CFAMM00407570 CHEMBL212920 Bioactive AGN-PC-0763NA
CFAMM00407569 CHEMBL212469 Bioactive AGN-PC-0763ML

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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