CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11219
Family Name Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ligand (3R,3aR)-7,8-dimethoxy-3-[[4-[(E)-3-phenylbut-2-enyl]piperazin-1-yl]methyl]-1,3,3a,4-tetrahydro-[1,2]oxazolo[4,3-c]quinoline family
No. of Seeds 7 No. of Other Members 3
Family Centroid CFAMM00407592 Functional Category Bioactive
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Binder Superfamily 27
Class Class 4579

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Proto-oncogene tyrosine-protein kinase Src inhibitor SureCN525... 8 8
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand (5R)-... 2 0
Sodium-dependent serotonin transporter and Alpha-2C adrenergic... 2 2


External ID

Functional Category

Molecule Name

CFAMM00407594 CHEMBL2112985 Bioactive (3R,3aR)-7,8-dimethoxy-3-[[4-[(E)-2-methyl-3-phenylprop-2-enyl]piperazin-1-yl]methyl]-1,3,3a,4-tetrahydro-[1,2]oxazolo[4,3-c]quinoline
CFAMM00407593 CHEMBL2112983 Bioactive (3R,3aR)-7,8-dimethoxy-3-[[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]methyl]-1,3,3a,4-tetrahydro-[1,2]oxazolo[4,3-c]quinoline
CFAMM00407592 CHEMBL2112971 Bioactive (3R,3aR)-7,8-dimethoxy-3-[[4-[(E)-3-phenylbut-2-enyl]piperazin-1-yl]methyl]-1,3,3a,4-tetrahydro-[1,2]oxazolo[4,3-c]quinoline
CFAMM00407591 CHEMBL2112977 Bioactive (3R,3aR)-7,8-dimethoxy-5-methyl-3-[[4-[(E)-4-methyl-5-phenylpent-4-enyl]piperazin-1-yl]methyl]-3a,4-dihydro-3H-[1,2]oxazolo[4,3-c]quinoline
CFAMM00407590 CHEMBL2112969 Bioactive (3R,3aR)-3-[[4-[2-(4-fluorophenoxy)ethyl]piperazin-1-yl]methyl]-7,8-dimethoxy-1,3,3a,4-tetrahydro-[1,2]oxazolo[4,3-c]quinoline
CFAMM00407596 CHEMBL390718 Bioactive 7,8-dimethoxy-3-[[4-[(E)-2-methyl-3-phenylprop-2-enyl]piperazin-1-yl]methyl]-1,3,3a,4-tetrahydro-[1,2]oxazolo[4,3-c]quinoline
CFAMM00407595 CHEMBL2112976 Bioactive (3R,3aR)-7,8-dimethoxy-3-[[4-(naphthalen-2-ylmethyl)piperazin-1-yl]methyl]-1,3,3a,4-tetrahydro-[1,2]oxazolo[4,3-c]quinoline

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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