CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1122
Family Name Integrin alpha-V and Integrin beta-5 inhibitor SureCN6563167 family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00319693 Functional Category Bioactive
Superfamily Thromboxane A2 receptor Ligand Bibv 308 Superfamily
Class Class 960

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor M4 Ligand Tropicamide Family 3 73
Thromboxane A2 receptor Ligand Ridogrel Family 7 83
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Prothrombin Inhibitor Ximelegatran Family 8 157
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Mitogen-activated protein kinase 12 Inhibitor VX-702 Family 3 49
Thromboxane A2 receptor Ligand Bibv 308 Family 14 40
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Coagulation factor X Inhibitor Otamixaban Family 9 21
Histone deacetylase 1 Inhibitor Pyroxamide Family 4 13
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Class II cytokine receptor Ligand IL-10 Family 7 45
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Thromboxane-A synthase Inhibitor CGS-22652 Family 37 95
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... 2 6
Hydroxycarboxylic acid receptor 2 Ligand 2-(6-phenylhexyl)pyri... 4 11
Metabotropic glutamate receptor 5 Ligand 3-cyano-5-fluoro-n-(p... 2 9
Integrin beta-3 and Integrin alpha-V inhibitor SureCN547914 fa... 8 32
Integrin beta-3 and Integrin alpha-V inhibitor SureCN3888804 f... 11 13
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-quinolin... 6 8
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 2 1
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[6-m... 13 12
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6359092 f... 9 5
Renin inhibitor (3R)-4-[[(2S,5S)-1-cyclohexyl-3-hydroxy-6-meth... 3 4
B1 bradykinin receptor ligand AGN-PC-005XAO family 3 17
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-2-(benzene... 3 2
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 8 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 1
Carboxypeptidase B2 and Carboxypeptidase B inhibitor 3-(6-amin... 2 1
Integrin alpha-V and Integrin beta-6 inhibitor 3-[[2-[4-[(4-me... 4 3
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2S,4R)... 2 2
Integrin alpha-V and Integrin beta-6 inhibitor SureCN12259087 ... 3 4
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(3-fluor... 10 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-074ASN f... 2 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-074ASZ f... 5 0
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[4-(... 3 0
Cannabinoid receptor 2 ligand AGN-PC-07CRHA family 4 8
Cytochrome P450 2C19 inhibitor AGN-PC-07CPMJ family 1 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-[[2-[3... 4 0
heptanamide NP ZINC08740384 Family 7 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00319693 CHEMBL111401 Bioactive SureCN6563167
CFAMM00319698 CHEMBL113853 Bioactive SureCN6301794

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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